Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17066941 | 1.00 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL28973475 | 0.86 | KDM4E (0.68) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10381468 | 0.83 | ALDH1A1 (0.71) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30783416 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2794074 | 0.81 | ALDH1A1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL377486 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5984776 | 0.81 | KDM4E (0.64) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9535544 | 0.81 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12301950 | 0.80 | MEN1 (0.75) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL15709048 | 0.80 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677576-A | 3-chloro-substituted quinolinone derivative and preparation method thereof | 浙江树人学院 | 2023-02-03 | — | — | CN | disclosed |