Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NQO2 | P16083 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367071 | 1.00 | MEN1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL28973475 | 0.86 | KDM4E (0.68) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL10381468 | 0.83 | ALDH1A1 (0.71) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30783416 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL2794074 | 0.81 | ALDH1A1 (0.69) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL377486 | 0.81 | MEN1 (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL5984776 | 0.81 | KDM4E (0.64) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL9535544 | 0.81 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL12301950 | 0.80 | MEN1 (0.75) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL15709048 | 0.80 | KDM4E (1.00) | MEN1KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115677576-B | 3-Chloro-substituted quinolinone derivative and preparation method thereof | 浙江树人学院 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023067192-A1 | METHODS FOR IMPROVING ABIOTIC STRESS RESISTANCE | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2023-04-27 | — | — | WO | disclosed |
| CN-115677576-A | 3-chloro-substituted quinolinone derivative and preparation method thereof | 浙江树人学院 | 2023-02-03 | — | — | CN | disclosed |
| US-9944619-B2 | Compounds for the treatment of HIV | GILEAD SCIENCES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170137405-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES, INC. | 2017-05-18 | — | — | US | disclosed |
| WO-2016022915-A1 | 6-SULFONYLAMINO QUINOLINE COMPOUNDS AS PLANT GROWTH REGULATORS | THE REGENT OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-11 | — | — | WO | disclosed |
| EP-2729448-B1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES INC (US) | 2015-09-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137405-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | CCR5, NPC1, FURIN | MEN1 2645/4885KMT2A 2804/4885KDM4E 1590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.