Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 2/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.65 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.65 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.65 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8397227 | 0.97 | CHRM1 (0.62) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL2606265 | 0.91 | ALDH1A1 (0.59) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL3902989 | 0.91 | CHRM1 (0.56) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL20123407 | 0.89 | CHRM1 (0.54) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL13407448 | 0.87 | CHRM1 (0.58) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| Hydrochloric Acid SCHEMBL31452986 | 0.87 | CHRM1 (0.52) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL6840449 | 0.85 | CHRM1 (0.50) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL15148101 | 0.85 | CHRM1 (0.50) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL7061351 | 0.84 | GAA (0.50) | CHRM1CHRM2CHRM4CHRM5CHRNB2 | |
| SCHEMBL13123174 | 0.83 | DNM1 (0.66) | CHRM1CHRM2CHRM4CHRM5CHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651237-A4 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | JOHNSON & JOHNSON CONSUMER (US) | 2008-10-01 | — | — | EP | claimed |
| EP-1651237-A2 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | Galileo Pharmaceuticals, Inc. (US) | 2006-05-03 | — | — | EP | claimed |
| WO-2005016270-A2 | METHODS FOR TREATMENT OF DERMATOLOGICAL CONDITIONS | GALILEO PHARMACEUTICALS, INC. (US) | 2005-02-24 | — | — | WO | claimed |
| US-20050032751-A1 | Methods for treatment of dermatological conditions | JOHNSON & JOHNSON CONSUMER INC. | 2005-02-10 | — | — | US | claimed |
| EP-0830336-B1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | CROMPTON CORP (US) | 2003-05-21 | — | — | EP | claimed |
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | claimed |
| EP-0748310-B1 | DIESTERS OF CARBONIC ACID ENDOWED WITH ANTIVIRAL AND ANTI-INFLAMMATORY ACTIVITY | ITALFARMACO SPA (IT) | 1999-06-02 | — | — | EP | claimed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | claimed |
| US-5686643-A | FOR PRODUCING POLYURETHANES OR POLYUREAS | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1997-11-11 | — | — | US | claimed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | claimed |
| US-5563288-A | REACTING DIMETHYL CARBONATE WITH ALCOHOL TO FORM METHYL ALKYL CARBONATE, REACTING CARBONATE WITH TERTIARY ALKANOLAMINE | OSI SPECIALTIES, INC. (US) | 1996-10-08 | — | — | US | claimed |
| EP-0476785-B1 | Processes for the preparation of aminoethers | OSI SPECIALTIES INC (US) | 1995-12-06 | — | — | EP | claimed |
| EP-0640388-A1 | Magnesium/aluminum mixed oxide catalysts and their use in the production of aminoethers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| US-5214142-A | PROCESSES FOR THE PREPARATION OF AMINOETHERS | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-05-25 | — | — | US | claimed |
| EP-0476785-A1 | Processes for the preparation of aminoethers | OSi Specialties, Inc. (US) | 1992-03-25 | — | — | EP | claimed |
| EP-3891751-A1 | QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION | Senda Biosciences, Inc. (US) | 2021-10-13 | — | — | EP | disclosed |
| EP-2903614-B1 | NOVEL COMPOUNDS, THEIR SYNTHESIS AND THEIR USES | SPHAERA PHARMA PTE LTD (SG) | 2021-09-29 | — | — | EP | disclosed |
| US-4845234-A | IN SITU LINING OF PIPE INTERIORS, CURING AGENTS FOR EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1989-07-04 | — | — | US | disclosed |
| US-4772695-A | DEHYDROHALOGENATION, INSECTICIDES | SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) | 1988-09-20 | — | — | US | disclosed |
| US-4762585-A | EPOXY RESINS WITH AMINE CURING AGENTS | CIBA-GEIGY CORPORATION (US) | 1988-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032751-A1 | Methods for treatment of dermatological conditions | KRT18, CUTA, TUBB1 | CHRM1 4334/4885CHRM2 3645/4885CHRM4 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.