SCHEMBL13407448

SCHEMBL13407448

COC(=O)OCCN(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.58
CHRM2 P08172 1/20 0.58
CHRM4 P08173 1/20 0.58
CHRM5 P08912 1/20 0.58
CHRNB2 P17787 1/20 0.58
CHRM3 P20309 1/20 0.58
CHRNA4 P43681 1/20 0.58
DNM1 Q05193 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
BCHE P06276 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
PHLPP2 Q6ZVD8 1/20 0.43
ALDH1A1 P00352 3/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 2/20 0.41
NPSR1 Q6W5P4 1/20 0.40
CYP1A2 P05177 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3036708 0.87 CHRM1 (0.65) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL19114956 0.86 GAA (0.46) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL6313803 0.86 MEN1 (0.46) CHRM1CHRM2CHRM4CHRM5CHRNB2
Hydrochloric Acid SCHEMBL8397227 0.85 CHRM1 (0.62) CHRM1CHRM2CHRM4CHRM5CHRNB2
Hydrochloric Acid SCHEMBL29812700 0.85 TSHR (0.45) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL16844976 0.85 CHRM2 (0.42) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL65053 0.83 SCN5A (0.39) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL15689451 0.83 ALDH1A1 (0.44) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL7056593 0.80 CHRM1 (0.52) CHRM1CHRM2CHRM4CHRM5CHRNB2
SCHEMBL19123576 0.80 CHRNB2 (0.38) CHRM1CHRM2CHRM4CHRM5CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122055373-A Bridged tricyclic carbamoyl pyridone compounds and uses thereof 吉利德科学公司 2026-05-15 CN disclosed
WO-2023178299-A1 PRODRUGS OF GANAXOLONE MARINUS PHARMACEUTICALS, INC. (US) 2023-09-21 WO disclosed
EP-4223285-A2 METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST Novartis AG (CH) 2023-08-09 EP disclosed
EP-3169309-B1 METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST NOVARTIS AG (CH) 2023-05-10 EP disclosed
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-10-06 US disclosed
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-08-04 US disclosed
US-20170196809-A1 METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2017-07-13 US disclosed
US-20170196979-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2017-07-13 US disclosed
US-7692026-B2 crystal structure; photosensitivity; cyan couplers FUJIFILM CORPORATION (JP) 2010-04-06 US disclosed
US-7692026-B2 crystal structure; photosensitivity; cyan couplers FUJIFILM CORPORATION (JP) 2010-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170196809-A1 METHOD OF ENCAPSULATING A NUCLEIC ACID IN A LIPID NANOPARTICLE HOST POLN, POLRMT, RNGTT CHRM1 4884/4885CHRM2 4880/4885CHRM4 4859/4885
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 CHRM1 2163/4885CHRM2 2684/4885CHRM4 2409/4885
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 CHRM1 2163/4885CHRM2 2684/4885CHRM4 2409/4885
US-20170196979-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, LPAR1, LPAR4 CHRM1 2163/4885CHRM2 2684/4885CHRM4 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.