Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 9/20 | 0.60 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.55 |
| ▸ | WNT1 | P04628 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.55 |
| ▸ | CLK2 | P49760 | 1/20 | 0.55 |
| ▸ | CLK3 | P49761 | 1/20 | 0.55 |
| ▸ | ROCK1 | Q13464 | 6/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.48 |
| ▸ | PRKACA | P17612 | 4/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367148 | 0.90 | WNT3A (0.59) | WNT3AROCK1CYP3A4PRKACAROCK2 | |
| SCHEMBL30366863 | 0.89 | WNT3A (0.61) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30367160 | 0.89 | WNT3A (0.59) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL31050200 | 0.88 | WNT3A (0.57) | WNT3AROCK1CYP3A4PRKACAROCK2 | |
| SCHEMBL30366883 | 0.85 | WNT3A (0.68) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30366861 | 0.81 | MAPT (0.58) | WNT3AROCK1CYP3A4PRKACAROCK2 | |
| SCHEMBL30366865 | 0.80 | RXRA (0.56) | ROCK1CYP3A4PRKACAROCK2 | |
| SCHEMBL22953924 | 0.80 | MAPK8 (0.62) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30367057 | 0.78 | WNT3A (0.57) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30366978 | 0.77 | WNT3A (0.56) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |