Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.56 |
| ▸ | ROCK1 | Q13464 | 11/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.53 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.49 |
| ▸ | CDK2 | P24941 | 1/20 | 0.49 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 6/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | RIOK2 | Q9BVS4 | 3/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31050200 | 0.93 | WNT3A (0.57) | RXRAROCK1CYP3A4CCNA2CDK2 | |
| SCHEMBL30366861 | 0.91 | MAPT (0.58) | ROCK1CYP3A4CCNA2CDK2CCNA1 | |
| SCHEMBL30367096 | 0.88 | RXRA (0.61) | RXRAMAPTRIOK2GSK3AMAPK10 | |
| SCHEMBL30366740 | 0.86 | RXRA (0.58) | RXRAROCK1CCNA2CDK2CCNA1 | |
| SCHEMBL30367148 | 0.84 | WNT3A (0.59) | ROCK1CYP3A4CCNA2CDK2CCNA1 | |
| SCHEMBL30366978 | 0.81 | WNT3A (0.56) | RXRA | |
| SCHEMBL30576079 | 0.81 | MAPK10 (0.58) | CDK2RIOK2GSK3AMAPK10 | |
| SCHEMBL29083767 | 0.81 | RXRA (0.58) | RXRACCNA2CDK2CCNA1MAPT | |
| SCHEMBL30367152 | 0.80 | WNT3A (0.54) | RXRA | |
| SCHEMBL30367112 | 0.80 | WNT3A (0.60) | ROCK1CYP3A4PRKACAROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |