Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT3A | P56704 | 15/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.57 |
| ▸ | WNT1 | P04628 | 2/20 | 0.57 |
| ▸ | GSK3B | P49841 | 2/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.57 |
| ▸ | CLK3 | P49761 | 1/20 | 0.57 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.52 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.52 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.52 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.52 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.52 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366863 | 0.91 | WNT3A (0.61) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30366883 | 0.91 | WNT3A (0.68) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30367112 | 0.89 | WNT3A (0.60) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30366978 | 0.88 | WNT3A (0.56) | WNT3APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30367057 | 0.80 | WNT3A (0.57) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30367065 | 0.80 | WNT3A (0.66) | WNT3A | |
| SCHEMBL30367096 | 0.79 | RXRA (0.61) | WNT3ADYRK1AWNT1GSK3BCLK2 | |
| SCHEMBL30367148 | 0.78 | WNT3A (0.59) | WNT3A | |
| SCHEMBL30366741 | 0.78 | WNT3A (0.63) | WNT3A | |
| SCHEMBL30367152 | 0.78 | WNT3A (0.54) | WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |