Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.61 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.45 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.45 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366978 | 0.92 | WNT3A (0.56) | RXRAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL30366740 | 0.89 | RXRA (0.58) | RXRAWNT3AMEN1KMT2AMAPK14 | |
| SCHEMBL30366865 | 0.88 | RXRA (0.56) | RXRAMAPTGSK3AMAPK10RIOK2 | |
| SCHEMBL30366946 | 0.83 | RXRA (0.82) | RXRAMAPTMEN1RAB9AKMT2A | |
| SCHEMBL30366741 | 0.83 | WNT3A (0.63) | RXRAWNT3A | |
| SCHEMBL30367152 | 0.82 | WNT3A (0.54) | RXRAWNT3A | |
| SCHEMBL30367158 | 0.82 | RXRA (0.66) | RXRAL3MBTL1WNT3AMEN1RAB9A | |
| SCHEMBL31050200 | 0.81 | WNT3A (0.57) | RXRAMAPTWNT3AITGB2ICAM1 | |
| SCHEMBL30366840 | 0.80 | TRPV1 (0.50) | RXRAMAPTWNT3ARAB9AMAPK14 | |
| SCHEMBL30366861 | 0.79 | MAPT (0.58) | MAPTWNT3AGSK3AMAPK10RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |