Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 2/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP3 | P08254 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29052438 | 0.79 | NAMPT (0.43) | NAMPTCCR1KCNH2HRH3NPC1 | |
| SCHEMBL30367699 | 0.77 | KDM1A (0.41) | NAMPTKDM1ACCR1 | |
| SCHEMBL30367031 | 0.76 | NAMPT (0.43) | NAMPTQDPRCCR1KCNH2HRH3 | |
| SCHEMBL30367315 | 0.75 | NAMPT (0.45) | NAMPTQDPRCCR1KCNH2HRH3 | |
| SCHEMBL14197130 | 0.74 | NAMPT (0.58) | NAMPTQDPRCCR1KCNH2HRH3 | |
| SCHEMBL30366906 | 0.73 | NAMPT (0.45) | NAMPTQDPRCCR1NPC1ALDH1A1 | |
| SCHEMBL30367405 | 0.72 | NAMPT (0.41) | NAMPTQDPRCCR1KCNH2HRH3 | |
| SCHEMBL30367544 | 0.71 | NAMPT (0.46) | NAMPTQDPRCCR1MMP2MMP3 | |
| SCHEMBL30367241 | 0.71 | NAMPT (0.43) | NAMPTQDPRCCR1KCNH2HRH3 | |
| SCHEMBL27694889 | 0.70 | NAMPT (0.55) | NAMPTQDPRCCR1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |