Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 6/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | QDPR | P09417 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367315 | 0.91 | NAMPT (0.45) | NAMPTALDH1A1LMNAIKBKBMET | |
| SCHEMBL30367298 | 0.73 | NAMPT (0.48) | NAMPTALDH1A1QDPRCCR1MAPT | |
| SCHEMBL30367544 | 0.70 | NAMPT (0.46) | NAMPTALDH1A1MEN1KMT2AQDPR | |
| SCHEMBL31488994 | 0.70 | NAMPT (0.54) | NAMPTSLC6A3ALDH1A1LMNAMEN1 | |
| SCHEMBL30366893 | 0.69 | MAPT (0.44) | NAMPTALDH1A1MAPTRAB9A | |
| SCHEMBL30367401 | 0.69 | NAMPT (0.36) | NAMPTALDH1A1LMNAIKBKBMAPT | |
| SCHEMBL30367672 | 0.69 | NAMPT (0.38) | NAMPTALDH1A1LMNAIKBKBMAPT | |
| SCHEMBL30367867 | 0.67 | KDM4E (0.40) | NAMPTALDH1A1CCR1MAPK1 | |
| SCHEMBL31489057 | 0.67 | QDPR (0.44) | NAMPTSLC6A3ALDH1A1LMNAMEN1 | |
| SCHEMBL5659741 | 0.67 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |