Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | FASN | P49327 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367867 | 0.85 | KDM4E (0.40) | TLR9TLR8NAMPTEPHX2FASN | |
| SCHEMBL30367623 | 0.84 | PDE4B (0.36) | KDM1ACYP3A4CYP2C9SLC9A1TLR9 | |
| SCHEMBL30367298 | 0.77 | NAMPT (0.48) | KDM1ANAMPTCCR1 | |
| SCHEMBL30367384 | 0.75 | MAPK1 (0.40) | TLR9TLR8NAMPTTYRO3MAPK1 | |
| SCHEMBL29052444 | 0.75 | KDM4E (0.41) | CYP3A4CYP2C9SLC9A1NAMPTMCHR1 | |
| SCHEMBL30367356 | 0.73 | DGAT1 (0.42) | TLR9TLR8NAMPTMAPK1DGAT1 | |
| SCHEMBL30367296 | 0.72 | MAPK1 (0.39) | TLR9TLR8NAMPTTYRO3CCR1 | |
| SCHEMBL30367399 | 0.72 | TLR9 (0.42) | TLR9TLR8MAPK1DGAT1 | |
| SCHEMBL30367001 | 0.68 | DGAT1 (0.39) | CYP3A4CYP2C9SLC9A1TLR9TLR8 | |
| SCHEMBL27392379 | 0.68 | NAMPT (0.45) | CYP3A4CYP2C9SLC9A1TLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |