Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22358962 | 0.88 | NAMPT (0.38) | NAMPTHSD17B10L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL30367780 | 0.87 | L3MBTL3 (0.47) | NAMPTHSD17B10KDM1AL3MBTL3L3MBTL1 | |
| SCHEMBL30367831 | 0.84 | HSD17B10 (0.56) | NAMPTHSD17B10L3MBTL3L3MBTL1ALDH1A1 | |
| SCHEMBL14151578 | 0.83 | NAMPT (0.35) | NAMPT | |
| SCHEMBL30553460 | 0.83 | SPR (0.40) | USP2HSD11B1SPR | |
| SCHEMBL19971641 | 0.82 | HSD17B10 (0.42) | NAMPTHSD17B10KDM1AL3MBTL3L3MBTL1 | |
| SCHEMBL20669201 | 0.80 | ALDH1A1 (0.44) | NAMPTHSD17B10ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL22158069 | 0.79 | SPR (0.47) | USP2HSD11B1SPR | |
| SCHEMBL22634389 | 0.79 | HSD11B1 (0.46) | USP2HSD11B1SPR | |
| SCHEMBL20765032 | 0.78 | L3MBTL3 (0.46) | NAMPTHSD17B10L3MBTL3L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064370-A1 | SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND USE THEREOF | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2023-04-20 | — | — | WO | disclosed |