Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B14 | Q9BPX1 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.53 |
| ▸ | CTSA | P10619 | 1/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | RPA1 | P27694 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137226 | 1.00 | HSD17B14 (0.57) | HSD17B14KDM4EALOX15TSHRACMSD | |
| SCHEMBL365163 | 0.91 | SCN9A (0.67) | SCN9A | |
| SCHEMBL3207980 | 0.85 | KDM4E (0.59) | HSD17B14KDM4EALOX15TSHRACMSD | |
| SCHEMBL208097 | 0.85 | KDM4E (0.64) | HSD17B14KDM4EALOX15TSHRACMSD | |
| SCHEMBL18287241 | 0.84 | HSD17B14 (0.56) | HSD17B14SCN9ACTSA | |
| SCHEMBL28876906 | 0.84 | SCN9A (0.62) | HSD17B14SCN9A | |
| Hydrochloric Acid SCHEMBL29133274 | 0.83 | KDM4E (0.61) | HSD17B14KDM4EALOX15TSHRACMSD | |
| SCHEMBL30900591 | 0.83 | KMO (0.63) | HSD17B14KDM4EALOX15TSHRACMSD | |
| SCHEMBL3054255 | 0.83 | KMO (0.63) | HSD17B14KDM4EALOX15TSHRACMSD | |
| SCHEMBL31301301 | 0.82 | CNR2 (0.56) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003406-B | Heteroaryl ring nitroxide compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2024-01-23 | — | — | CN | disclosed |
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| CN-116003406-A | Heteroaryl ring nitroxide compound and preparation method and application thereof | 北京鞍石生物科技有限责任公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |