Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.63 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HSD17B14 | Q9BPX1 | 4/20 | 0.49 |
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.46 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3054255 | 1.00 | KMO (0.63) | KMOCNR2CNR1KDM4EALOX15 | |
| SCHEMBL31061831 | 0.89 | KMO (0.54) | KMOCNR2CNR1KDM4EHSD17B14 | |
| SCHEMBL30367705 | 0.83 | HSD17B14 (0.57) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL1137226 | 0.83 | HSD17B14 (0.57) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL208097 | 0.82 | KDM4E (0.64) | KMOCNR2CNR1KDM4EALOX15 | |
| SCHEMBL28559901 | 0.81 | KMO (0.62) | KMOKDM4EALOX15TSHRACMSD | |
| SCHEMBL3642571 | 0.81 | HSD17B14 (0.62) | CNR2KDM4EALOX15TSHRACMSD | |
| Hydrochloric Acid SCHEMBL29133274 | 0.80 | KDM4E (0.61) | KMOCNR2CNR1KDM4EALOX15 | |
| SCHEMBL3057779 | 0.80 | CNR2 (0.69) | KMOCNR2CNR1KDM4EALOX15 | |
| SCHEMBL29470232 | 0.80 | MEN1 (0.58) | KMOKDM4EHPGDSMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204009-B | Modulators of integrated stress pathways | 卡里科生命科学有限责任公司 | 2024-05-07 | — | — | CN | disclosed |