SCHEMBL30368263

SCHEMBL30368263

Oc1cc(C(F)(F)F)c(C(F)(F)F)cc1C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 3/20 0.46
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP1A2 P05177 1/20 0.46
MAPT P10636 1/20 0.46
ATP2A2 P16615 1/20 0.46
ATP2A3 Q93084 1/20 0.46
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 2/20 0.37
MCL1 Q07820 1/20 0.36
KIF11 P52732 1/20 0.35
TP53 P04637 2/20 0.33
CYP3A4 P08684 2/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
AR P10275 3/20 0.32
APP P05067 1/20 0.32
CES2 O00748 2/20 0.32
TSHR P16473 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10357875 1.00 ALOX15 (0.46) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL5514137 0.94 ALOX15 (0.50) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL5508813 0.91 ALDH1A1 (0.41) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL6754916 0.80 POLB (0.41) ALDH1A1KIF11CES2TSHRTDP1
SCHEMBL5522928 0.79 CA12 (0.44) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL5515400 0.79 CA12 (0.39) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL18893875 0.78 KIF11 (0.42) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL9297350 0.78 ALOX15 (0.48) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL23542367 0.76 ALDH1A1 (0.59) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2
SCHEMBL15256022 0.74 LMNA (0.47) ALOX15ALDH1A1SMN1; SMN2KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082563-B (Meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2024-09-20 CN disclosed
CN-118359760-A Optical resin, optical element, and optical device 株式会社 尼康 2024-07-19 CN disclosed
CN-116082563-A (meth) acrylate compound, optical resin additive, optical element, and optical device 株式会社 尼康 2023-05-09 CN disclosed