SCHEMBL30368992

SCHEMBL30368992

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nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CTSD P07339 11/20 0.47
NTSR2 O95665 1/20 0.45
NTSR1 P30989 1/20 0.45
FURIN P09958 1/20 0.45
PCSK6 P29122 1/20 0.45
REN P00797 1/20 0.43
CPB2 Q96IY4 1/20 0.43
ENPEP Q07075 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30369179 0.93 CTSD (0.48) CTSDNTSR2NTSR1FURINPCSK6
SCHEMBL30578954 0.91 CPB2 (0.47) CPB2ENPEP
SCHEMBL31514354 0.90 RXFP1 (0.46) CTSDFURINPCSK6
SCHEMBL29625510 0.90 NTSR2 (0.48) CTSDNTSR2NTSR1FURINPCSK6
SCHEMBL29464043 0.89 CCNA2 (0.43) CTSDNTSR2NTSR1FURINPCSK6
SCHEMBL29500572 0.89 CCNA2 (0.43) CTSDNTSR2NTSR1FURINPCSK6
SCHEMBL29489272 0.88 CPB2 (0.45) FURINCPB2ENPEP
SCHEMBL31574021 0.86 ENPEP (0.51) ENPEP
SCHEMBL31063765 0.85 ENPEP (0.49) NTSR2NTSR1CPB2ENPEP
SCHEMBL31041715 0.85 FURIN (0.46) CTSDFURINREN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4159745-B1 S100A8-INHIBITING PEPTIDE AND THERAPEUTIC DRUG FOR DISEASE WHICH CONTAINING SAME UNIV TOKYO WOMENS MEDICAL (JP) 2025-09-24 EP disclosed
US-20230220005-A1 S100A8-INHIBITING PEPTIDE AND DISEASE THERAPEUTIC AGENT CONTAINING SAME TOKYO WOMEN'S MEDICAL UNIVERSITY (JP) 2023-07-13 US disclosed
EP-4159745-A1 S100A8-INHIBITING PEPTIDE AND THERAPEUTIC DRUG FOR DISEASE WHICH CONTAINING SAME Tokyo Women's Medical University (JP) 2023-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230220005-A1 S100A8-INHIBITING PEPTIDE AND DISEASE THERAPEUTIC AGENT CONTAINING SAME S100A8, S100A11, S100A4 CTSD 1443/4885NTSR2 1314/4885NTSR1 1150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.