Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1282763 | 0.87 | SMN1; SMN2 (0.43) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL2206945 | 0.79 | SMN1; SMN2 (0.46) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL442966 | 0.78 | SMN1; SMN2 (0.45) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL1147479 | 0.78 | SMN1; SMN2 (0.45) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL398929 | 0.78 | PKLR (0.42) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL1282206 | 0.77 | SMN1; SMN2 (0.42) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL24192983 | 0.77 | TSHR (0.39) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL30229162 | 0.77 | TSHR (0.39) | TSHRALOX15USP2SMN1; SMN2ADORA1 | |
| SCHEMBL3042049 | 0.77 | GPR119 (0.40) | TSHRALOX15USP2SMN1; SMN2HTT | |
| SCHEMBL619446 | 0.77 | SMN1; SMN2 (0.44) | TSHRALOX15USP2SMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | CCR2, CCR1, CCR5 | TSHR 1158/4885ALOX15 1072/4885USP2 3932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.