Framycetin

Framycetin

SCHEMBL3037

NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O.NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O.NCC1OC(OC2C(N)CC(N)C(O)C2O)C(N)C(O)C1O.O=S(=O)(O)O.O=S(=O)(O)O.O=S(=O)(O)O

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Framycetin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.92
RECQL P46063 1/20 0.92
TDP1 Q9NUW8 1/20 0.92
LRAT O95237 2/20 0.84
MEN1 O00255 1/20 0.84
TRPV1 Q8NER1 1/20 0.84
HSD17B10 Q99714 1/20 0.82
TSHR P16473 1/20 0.82
LMNA P02545 1/20 0.74
MAPT P10636 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Framycetin SCHEMBL2133931 0.97 BLM (0.98) BLMRECQLTDP1LRATMEN1
Framycetin SCHEMBL285111 0.97 BLM (0.98) BLMRECQLTDP1LRATMEN1
Framycetin SCHEMBL29628935 0.97 BLM (0.98) BLMRECQLTDP1LRATMEN1
Framycetin SCHEMBL2133938 0.97 BLM (0.98) BLMRECQLTDP1LRATMEN1
Framycetin SCHEMBL373681 0.97 BLM (0.98) BLMRECQLTDP1LRATMEN1
Framycetin SCHEMBL3696748 0.97 BLM (0.98) BLMRECQLTDP1LRATMEN1
Paromomycin SCHEMBL3355 0.96 BLM (1.00) BLMRECQLTDP1LRATMEN1
Paromomycin SCHEMBL691558 0.96 BLM (1.00) BLMRECQLTDP1LRATMEN1
Paromomycin SCHEMBL2527138 0.96 BLM (1.00) BLMRECQLTDP1LRATMEN1
Paromomycin SCHEMBL1680052 0.96 BLM (1.00) BLMRECQLTDP1LRATMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 10278 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122005954-A Antioxidant and antibacterial sexual collagen repair film 山东博达医疗用品股份有限公司 2026-05-12 CN claimed
US-20260103492-A1 CYCLOSPORINE COMPOSITIONS AND METHODS OF USE BACAINN BIOTHERAPEUTICS, LTD. (KY) 2026-04-16 US claimed
US-20250367139-A1 COMPOUND HYDROCORTISONE AND NEOMYCIN SULFATE GRANULE AND PREPARATION METHOD THEREOF HEBEI CHANGTIAN PHARMACEUTICAL CO LTD (CN) 2025-12-04 US claimed
US-20250312046-A1 LIGATION CLIP AND PREPARATION METHOD THEREOF SICHUAN GUONA TECHNOLOGY CO., LTD. (CN) 2025-10-09 US claimed
EP-4628110-A1 LIGATING CLIP Chengdu Guona Technology Co., Ltd (CN) 2025-10-08 EP claimed
US-12421281-B2 Cyclosporine compositions and methods of use BACAINN BIOTHERAPEUTICS, LTD. (KY) 2025-09-23 US claimed
US-20250277175-A1 SINGLE-CHAMBER MICROBIAL ELECTROLYSIS CELL SYSTEM WITHOUT ION EXCHANGE MEMBRANE AND METHOD FOR PRODUCING CLEAN GAS SUCH AS HYDROGEN AND BIOGAS USING SAME PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2025-09-04 US claimed
US-20250268978-A1 TOPICAL CREAM AND METHOD OF USE WellSpring and Company LLC (US) 2025-08-28 US claimed
EP-3876904-B1 ORAL MUCOSAL CARRIER AND PROTECTANT INSPIRED MAT STRATEGIES LLC (US) 2025-08-20 EP claimed
US-20250248940-A1 Biopolymer Formulations for Drug Delivery 11584022 CANADA INC. (CA) 2025-08-07 US claimed
US-4136173-A VEHICLES FOR OPHTHALMIC DRUGS AMERICAN HOME PRODUCTS CORP. (US) 1979-01-23 US claimed
US-4122158-A FOR TREATMENT OF BURNS; BIODEGRADABLE HYDROPHOBIC POLYMER; SUSTAINED RELEASE ALZA CORPORATION (US) 1978-10-24 US claimed
US-4100271-A Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes COOPER LABORATORIES, INC. (US) 1978-07-11 US claimed
US-4035146-A CELLULOSE, STARCHES, LEATHER SCHWARZ SERVICES INTERNATIONAL LTD. (US) 1977-07-12 US claimed
US-4024871-A POLYURETHANE ETHICON, INC. (US) 1977-05-24 US claimed
US-4013792-A BETAMETHASONE BENZOATE AND NEOMYCIN SULFATE IN ALCOHOLCELLULOSE-SODIUM CHLORIDE GEL WARNER-LAMBERT COMPANY (US) 1977-03-22 US claimed
US-3987797-A ANTIMICROBIAL SUTURES ETHICON, INC. (US) 1976-10-26 US claimed
US-3983209-A HYDROPHOBIC BIOERODIBLE POLYMER, MICROBIOCIDE OR PROTEOLYTIC ENZYME ALZA CORPORATION (US) 1976-09-28 US claimed
US-3980778-A Anti-inflammatory steroid THE UPJOHN COMPANY (US) 1976-09-14 US claimed
US-3949077-A PRIMYCIN, NEOMYCIN SULFATE, OXYTETRACYCLINE CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT (HU) 1976-04-06 US claimed