SCHEMBL3037090

SCHEMBL3037090

COC1(OC)C=CC(C(=O)c2ccccc2)C(O)=C1O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.36
EPHX1 P07099 3/20 0.35
CES1 P23141 2/20 0.34
SRC P12931 1/20 0.34
HTT P42858 3/20 0.33
ALDH1A1 P00352 3/20 0.33
CYP1A2 P05177 2/20 0.33
HPGD P15428 2/20 0.33
CYP2C19 P33261 2/20 0.33
SLC6A3 Q01959 2/20 0.33
LMNA P02545 1/20 0.33
PGR P06401 1/20 0.33
CYP2D6 P10635 1/20 0.33
SLC6A2 P23975 1/20 0.33
PDE4A P27815 1/20 0.33
MAPK1 P28482 1/20 0.33
HRH1 P35367 1/20 0.33
PDE4D Q08499 1/20 0.33
KMT2A Q03164 3/20 0.33
ALOX15 P16050 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2639855 0.78 MAPT (0.36) TSHREPHX1CES1HTTALDH1A1
SCHEMBL3120601 0.73 TSHR (0.36) TSHREPHX1CES1SRCHTT
SCHEMBL344146 0.73 HTT (0.38) TSHREPHX1CES1SRCHTT
SCHEMBL8172322 0.72 TSHR (0.35) TSHREPHX1CES1SRCHTT
SCHEMBL9732807 0.71 TSHR (0.34) TSHREPHX1CES1SRCHTT
SCHEMBL180232 0.71 TSHR (0.34) TSHREPHX1CES1SRCHTT
SCHEMBL7855173 0.71 TSHR (0.34) TSHREPHX1CES1SRCHTT
SCHEMBL10823202 0.70 ALDH1A1 (0.33) TSHREPHX1CES1SRCHTT
SCHEMBL5918221 0.69 CES2 (0.48) TSHRCES1KMT2ACES2MAPT
SCHEMBL8166850 0.69 TSHR (0.32) TSHREPHX1CES1SRCHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1748382-B1 Integrated circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KK (JP) 2010-07-07 EP disclosed
EP-1903481-B1 Integrated circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KK (JP) 2009-10-28 EP disclosed
US-7598874-B2 Integrated-circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 2009-10-06 US disclosed
EP-1411465-B1 RETROREFLECTIVE PRODUCT IN WHICH INTEGRATED CIRCUIT IS SEALED NIPPON CARBIDE KOGYO KK (JP) 2008-08-06 EP disclosed
EP-1903481-A1 Integrated circuit enclosed retroreflective product Nippon Carbide Kogyo Kabushiki Kaisha (JP) 2008-03-26 EP disclosed
US-20070194133-A1 INTEGRATED-CIRCUIT ENCLOSED RETROREFLECTIVE PRODUCT NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 2007-08-23 US disclosed
US-7224279-B2 Integrated circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 2007-05-29 US disclosed
EP-1748382-A2 Integrated circuit enclosed retroreflective product Nippon Carbide Kogyo Kabushiki Kaisha (JP) 2007-01-31 EP disclosed
US-20040218273-A1 Integrated circuit enclosed retroreflective product NIPPON CARBIDE KOGYO KABUSHIKI KAISHA (JP) 2004-11-04 US disclosed
EP-1411465-A1 RETROREFLECTIVE PRODUCT IN WHICH INTEGRATED CIRCUIT IS SEALED Nippon Carbide Kogyo Kabushiki Kaisha (JP) 2004-04-21 EP disclosed