Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | ADH1B | P00325 | 3/20 | 0.33 |
| ▸ | ADH1C | P00326 | 3/20 | 0.33 |
| ▸ | ADH1A | P07327 | 3/20 | 0.33 |
| ▸ | ADH7 | P40394 | 3/20 | 0.33 |
| ▸ | ADH4 | P08319 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL385559 | 0.79 | TSHR (0.40) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| Hydrochloric Acid SCHEMBL29133121 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| SCHEMBL3030523 | 0.78 | TSHR (0.39) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| SCHEMBL28669358 | 0.77 | CTSK (0.32) | TSHRSMN1; SMN2CTSK | |
| SCHEMBL28012234 | 0.74 | TSHR (0.36) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| SCHEMBL3042552 | 0.73 | ADH1B (0.42) | TSHRSMN1; SMN2ADH1BADH1CADH1A | |
| SCHEMBL3040110 | 0.73 | CYP3A4 (0.41) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| SCHEMBL9120387 | 0.73 | TSHR (0.39) | TSHRSMN1; SMN2CTSKADH1BADH1C | |
| SCHEMBL20723704 | 0.73 | TSHR (0.39) | TSHRSMN1; SMN2CTSKFDPSCYP3A4 | |
| SCHEMBL96308 | 0.73 | CYP3A4 (0.55) | TSHRSMN1; SMN2CYP3A4L3MBTL1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100216736-A2 | 2'-CYANOPYRIMIDINE NUCLEOSIDE COMPOUND | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2010-08-26 | — | — | US | disclosed |
| US-20100056466-A1 | 2'-Cyanopyrimidine Nucleoside Compound | MATSUDA, AKIRA (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2045256-A1 | 2'-CYANOPYRIMIDINE NUCLEOSIDE COMPOUND | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 2009-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216736-A2 | 2'-CYANOPYRIMIDINE NUCLEOSIDE COMPOUND | NUDT1, DPYD, SLC29A1 | TSHR 2498/4885SMN1; SMN2 1045/4885CTSK 4594/4885 |
| US-20100056466-A1 | 2'-Cyanopyrimidine Nucleoside Compound | NUDT1, DPYD, SLC29A1 | TSHR 2498/4885SMN1; SMN2 1045/4885CTSK 4594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.