SCHEMBL30375183

SCHEMBL30375183

CC(C)(c1ccc(C(Cc2ccc(O)c(C(F)(F)F)c2)c2ccc(O)c(C(F)(F)F)c2)cc1)c1ccc(O)c(C(F)(F)F)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.37
ESR1 P03372 5/20 0.36
KLF10 Q13118 1/20 0.36
ALOX15 P16050 4/20 0.35
ALOX12 P18054 4/20 0.35
PDE4A P27815 3/20 0.34
CYP19A1 P11511 2/20 0.33
ESRRG P62508 1/20 0.32
ALDH1A1 P00352 3/20 0.32
CYP3A4 P08684 3/20 0.32
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
TP53 P04637 2/20 0.32
HPGD P15428 2/20 0.32
MAPK1 P28482 2/20 0.32
RECQL P46063 2/20 0.32
KMT2A Q03164 2/20 0.32
HIF1A Q16665 2/20 0.32
HSD17B10 Q99714 2/20 0.32
CNR1 P21554 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30374574 0.90 RORC (0.38) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30375052 0.84 ESRRG (0.38) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30375004 0.80 SHBG (0.40) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30320269 0.79 ESR1 (0.56) RORCESR1KLF10ALOX15ALOX12
SCHEMBL3685920 0.78 ESR1 (0.57) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30374761 0.77 CA2 (0.40) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30374779 0.77 ALOX15 (0.52) RORCESR1KLF10ALOX15ALOX12
SCHEMBL30374820 0.76 ESR1 (0.47) RORCESR1KLF10PDE4ACYP3A4
SCHEMBL15968048 0.76 CYP2C9 (0.43) ESR1ALOX15ALOX12PDE4ACYP19A1
SCHEMBL30375009 0.76 ESR1 (0.48) RORCESR1KLF10PDE4AESRRG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed