SCHEMBL30375397

SCHEMBL30375397

Cc1cccnc1CBr.[O-][Br+2]([O-])O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS3 P29474 1/20 0.38
NOS1 P29475 1/20 0.38
NOS2 P35228 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.36
ALDH1A1 P00352 1/20 0.36
DAO P14920 1/20 0.36
PLAU P00749 1/20 0.36
KDM4E B2RXH2 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ADORA2A P29274 7/20 0.34
ADORA1 P30542 6/20 0.34
ADORA3 P0DMS8 1/20 0.34
ADORA2B P29275 1/20 0.34
MAPT P10636 2/20 0.34
P2RX7 Q99572 1/20 0.34
CTNNB1 P35222 1/20 0.34
WNT3A P56704 1/20 0.34
KMT2A Q03164 1/20 0.33
CYP1A2 P05177 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11702390 0.89
SCHEMBL29524973 0.89
Bromide SCHEMBL30250885 0.87 NOS3 (0.45) NOS3NOS1NOS2L3MBTL1ALDH1A1
SCHEMBL5729113 0.73 NOS3 (0.43) NOS3NOS1NOS2L3MBTL1ALDH1A1
SCHEMBL243610 0.72
SCHEMBL5024689 0.71 NOS3 (0.45) NOS3NOS1NOS2L3MBTL1ALDH1A1
Hydrochloric Acid SCHEMBL10765635 0.71 L3MBTL1 (0.57) NOS3NOS1NOS2L3MBTL1ALDH1A1
SCHEMBL91425 0.70
SCHEMBL28822555 0.70
SCHEMBL4038818 0.69 ALDH1A1 (0.45) NOS3NOS1NOS2L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010947-A Antagonists of adenosine A2a receptors 阿道尔克斯治疗有限公司 2026-05-12 CN disclosed
CN-115996929-A Antagonists of adenosine A2a receptors 阿道尔克斯治疗有限公司 2023-04-21 CN disclosed