Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 12/20 | 0.53 |
| ▸ | HTR1A | P08908 | 11/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | HTR7 | P34969 | 6/20 | 0.53 |
| ▸ | HTR6 | P50406 | 6/20 | 0.53 |
| ▸ | HTR2A | P28223 | 5/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25758322 | 1.00 | SLC6A4 (0.53) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL30375994 | 0.92 | KCNA5 (0.49) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL25759401 | 0.92 | KCNA5 (0.49) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL25759383 | 0.89 | KCNA5 (0.61) | SLC6A4DRD2HTR7HTR2AKCNA5 | |
| SCHEMBL30376202 | 0.89 | KCNA5 (0.61) | SLC6A4DRD2HTR7HTR2AKCNA5 | |
| SCHEMBL30375766 | 0.85 | KCNA5 (0.60) | SLC6A4DRD2HTR7HTR2AKCNA5 | |
| SCHEMBL25759431 | 0.85 | KCNA5 (0.60) | SLC6A4DRD2HTR7HTR2AKCNA5 | |
| SCHEMBL8876721 | 0.80 | HTR6 (0.62) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL23649454 | 0.79 | HTR1A (0.54) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL9031074 | 0.77 | HTR1A (0.47) | SLC6A4HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | claimed |
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | disclosed |
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |