Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 6/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | HTR7 | P34969 | 5/20 | 0.44 |
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25759401 | 1.00 | KCNA5 (0.49) | KCNA5KCNH2HTR6HTR1ASLC6A4 | |
| SCHEMBL25758322 | 0.92 | SLC6A4 (0.53) | KCNA5KCNH2HTR6HTR1ASLC6A4 | |
| SCHEMBL30375406 | 0.92 | SLC6A4 (0.53) | KCNA5KCNH2HTR6HTR1ASLC6A4 | |
| SCHEMBL30376202 | 0.89 | KCNA5 (0.61) | KCNA5KCNH2SLC6A4DRD2HTR7 | |
| SCHEMBL25759383 | 0.89 | KCNA5 (0.61) | KCNA5KCNH2SLC6A4DRD2HTR7 | |
| SCHEMBL25759431 | 0.85 | KCNA5 (0.60) | KCNA5KCNH2SLC6A4DRD2HTR7 | |
| SCHEMBL30375766 | 0.85 | KCNA5 (0.60) | KCNA5KCNH2SLC6A4DRD2HTR7 | |
| SCHEMBL23648880 | 0.79 | SLC2A1 (0.44) | HTR6HTR1ASLC6A4DRD2HTR7 | |
| SCHEMBL13285873 | 0.76 | HTR7 (0.56) | KCNA5KCNH2HTR7 | |
| SCHEMBL25286043 | 0.76 | ADRA1D (0.50) | KCNH2SLC6A4DRD2HTR7HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | claimed |
| CN-116157124-A | Sulfonamide derivative and pharmaceutical composition for preventing or treating mental diseases containing the same as active ingredient | 大邱庆北尖端医疗产业振兴财团 | 2023-05-23 | — | — | CN | disclosed |
| EP-4159718-A1 | SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2023-04-05 | — | — | EP | disclosed |