SCHEMBL30375445

SCHEMBL30375445

Cc1cc(Cc2cc(Cc3cc(Cc4cc(C)c(O)c(C)c4)c(O)c(O)c3O)c(O)c(O)c2O)cc(C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.53
HMGB1 P09429 1/20 0.46
CXCL12 P48061 1/20 0.46
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
PTGS1 P23219 3/20 0.41
PTGS2 P35354 3/20 0.41
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
HIF1A Q16665 2/20 0.41
CYP2D6 P10635 1/20 0.41
HSD17B10 Q99714 1/20 0.41
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
HSPA5 P11021 2/20 0.38
AMY1A P0DUB6 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 1/20 0.37
ALK Q9UM73 1/20 0.37
ALOX5 P09917 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3190810 1.00 SHBG (0.53) SHBGHMGB1CXCL12CA1CA2
SCHEMBL686771 0.98 SHBG (0.55) SHBGHMGB1CXCL12CA1CA2
SCHEMBL28684704 0.91 SHBG (0.53) SHBGHMGB1CXCL12CA1CA2
SCHEMBL4067177 0.87 SHBG (0.53) SHBGHMGB1CXCL12CA1CA2
SCHEMBL15800832 0.87 SHBG (0.53) SHBGHMGB1CXCL12CA1CA2
SCHEMBL17095067 0.85 SHBG (0.44) SHBGHMGB1CXCL12PTGS1PTGS2
Pyrogallol SCHEMBL17453322 0.85 TRPA1 (0.48) SHBGHMGB1CXCL12CA1CA2
SCHEMBL14462649 0.85 ESR1 (0.63) SHBGHMGB1CXCL12CA1CA2
SCHEMBL1269461 0.85 AMY1A (0.55) SHBGHMGB1CXCL12CA1CA2
SCHEMBL30374768 0.85 AMY1A (0.55) SHBGHMGB1CXCL12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed