Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.43 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31453996 | 0.90 | L3MBTL1 (0.43) | DCLRE1ADCLRE1BALDH1A1BCL2SMN1; SMN2 | |
| SCHEMBL455341 | 0.84 | CRHBP (0.45) | DCLRE1ADCLRE1BALDH1A1MAPK1BCL2 | |
| SCHEMBL3027303 | 0.82 | ALOX5 (0.39) | ALDH1A1SMN1; SMN2MEN1LMNAKMT2A | |
| SCHEMBL8540746 | 0.82 | ALDH1A1 (0.44) | DCLRE1ADCLRE1BALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20696572 | 0.82 | ALDH1A1 (0.44) | DCLRE1ADCLRE1BALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL30380433 | 0.81 | DCLRE1A (0.47) | DCLRE1ADCLRE1BALDH1A1BCL2SMN1; SMN2 | |
| SCHEMBL28992451 | 0.81 | DCLRE1A (0.47) | DCLRE1ADCLRE1BALDH1A1BCL2SMN1; SMN2 | |
| SCHEMBL18076562 | 0.80 | BACE1 (0.46) | DCLRE1ADCLRE1BALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL7617883 | 0.79 | GABRA1 (0.54) | DCLRE1ADCLRE1BALDH1A1MAPK1BCL2 | |
| SCHEMBL9618333 | 0.78 | SMN1; SMN2 (0.47) | DCLRE1ADCLRE1BBCL2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |