Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | CCKAR | P32238 | 3/20 | 0.47 |
| ▸ | CCKBR | P32239 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25991604 | 1.00 | ADAM17 (0.60) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL30279235 | 1.00 | ADAM17 (0.60) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL20280505 | 0.91 | L3MBTL1 (0.60) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL29401255 | 0.89 | ADAM17 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL22804050 | 0.89 | ADAM17 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL19206913 | 0.89 | L3MBTL1 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL29401320 | 0.89 | ADAM17 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL29400491 | 0.89 | ADAM17 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL10310207 | 0.89 | ADAM17 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR | |
| SCHEMBL4294679 | 0.89 | ADAM17 (0.58) | ADAM17L3MBTL1EPHX1CCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419124-A2 | MENAQUINONE-BINDING COMPOUNDS AND METHODS OF USE THEREOF | The Rockefeller University (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023070085-A2 | MENAQUINONE-BINDING COMPOUNDS AND METHODS OF USE THEREOF | THE ROCKEFELLER UNIVERSITY (US) | 2023-04-27 | — | — | WO | disclosed |