Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 3/20 | 0.50 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | CCKAR | P32238 | 3/20 | 0.49 |
| ▸ | CCKBR | P32239 | 3/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29401320 | 1.00 | ADAM17 (0.58) | ADAM17L3MBTL1CTSSCTSKACE | |
| SCHEMBL4294679 | 1.00 | ADAM17 (0.58) | ADAM17L3MBTL1CTSSCTSKACE | |
| SCHEMBL10310207 | 1.00 | ADAM17 (0.58) | ADAM17L3MBTL1CTSSCTSKACE | |
| SCHEMBL22804050 | 1.00 | ADAM17 (0.58) | ADAM17L3MBTL1CTSSCTSKACE | |
| SCHEMBL29401255 | 0.91 | ADAM17 (0.58) | ADAM17L3MBTL1CTSSCTSKCCKAR | |
| SCHEMBL18002447 | 0.91 | CTSS (0.50) | ADAM17L3MBTL1CTSSCTSKACE | |
| SCHEMBL29401597 | 0.91 | ADAM17 (0.58) | ADAM17L3MBTL1CTSSCTSKCCKAR | |
| SCHEMBL21309886 | 0.90 | L3MBTL1 (0.57) | ADAM17L3MBTL1CTSSCTSKCCKAR | |
| SCHEMBL29169598 | 0.90 | L3MBTL1 (0.57) | ADAM17L3MBTL1CTSSCTSKCCKAR | |
| SCHEMBL22804106 | 0.90 | ADAM17 (0.53) | ADAM17L3MBTL1ACECCKARCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112480122-B | Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof | 中山大学 | 2022-03-22 | — | — | CN | claimed |
| EP-4742904-A1 | CONJUGATES OF ANTIMICROBIAL AGENT AND A LINKER MOIETY SUITABLE FOR COVALENT ATTACHMENT TO MATERIALS AND SUBSTRATES | Amicoat AS (NO) | 2026-05-20 | — | — | EP | disclosed |
| US-20260103499-A1 | BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS | HAN JIE (US) | 2026-04-16 | — | — | US | disclosed |
| US-12528852-B2 | Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs | Han, Jie (US) | 2026-01-20 | — | — | US | disclosed |
| US-12466784-B2 | Analogs of pterostilbene amino acid bearing carbonates for treating a non-alcoholic fatty liver disease and nonalcoholic steatohepatitis | APICAL MOLECULAR BIOTECH CO., LTD. (TW) | 2025-11-11 | — | — | US | disclosed |
| US-20250332271-A1 | PROGRAMMABLE SELECTIVE ACYLATION OF POLYOLS | UNIV NANYANG TECH (SG) | 2025-10-30 | — | — | US | disclosed |
| EP-4136063-B1 | NOVEL ANALOGS OF PTEROSTILBENE AMINO ACID BEARING CARBONATES FOR TREATING A NON-ALCOHOLIC FATTY LIVER DISEASE AND NONALCOHOLIC STEATOHEPATITIS | APICAL MOLECULAR BIOTECH CO LTD (TW) | 2025-10-22 | — | — | EP | disclosed |
| US-12433845-B2 | Peptide-functionalized biodegradable polymers for efficient delivery of various RNAs | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2025-10-07 | — | — | US | disclosed |
| WO-2025016913-A1 | CONJUGATES OF ANTIMICROBIAL AGENT AND A LINKER MOIETY SUITABLE FOR COVALENT ATTACHMENT TO MATERIALS AND SUBSTRATES | AMICOAT AS (NO) | 2025-01-23 | — | — | WO | disclosed |
| CN-118930602-A | Method for performing terminal allylation modification on natural amino acid or polypeptide | 南京工业大学 | 2024-11-12 | — | — | CN | disclosed |
| CN-115521368-A | Exendin-4 derivatives | 江苏鸿永医药技术有限公司 | 2022-12-27 | — | — | CN | disclosed |
| US-11512071-B2 | Decarboxylative cross-coupling and applications thereof | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2022-11-29 | — | — | US | disclosed |
| CN-112043835-B | Bioreversible introducing group for nitrogen and hydroxyl-containing drugs | 韩捷 | 2022-10-21 | — | — | CN | disclosed |
| US-20220332781-A1 | GLUCAGON-RECEPTOR SELECTIVE POLYPEPTIDES AND METHODS OF USE THEREOF | I2O THERAPEUTICS, INC. | 2022-10-20 | — | — | US | disclosed |
| WO-2022185319-A1 | UBIQUITIN LIGASE KPC1-PEPTIDE BASED PROTEOLYSIS TARGETING CHIMERAS (PROTAC) AND USES THEREOF | TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) | 2022-09-09 | — | — | WO | disclosed |
| US-20220283131-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTES | BERTIS CO., LTD. (KR) | 2022-09-08 | — | — | US | disclosed |
| US-20220183990-A1 | PEPTIDE-FUNCTIONALIZED BIODEGRADABLE POLYMERS FOR EFFICIENT DELIVERY OF VARIOUS RNAS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-16 | — | — | US | disclosed |
| US-11285103-B2 | Degradable hydrogel under physiological conditions | HAN JIE (CN) | 2022-03-29 | — | — | US | disclosed |
| CN-112480122-B | Tetrahydroimidazo [1,2-a ] pyrazine compound, composition, preparation method and application thereof | 中山大学 | 2022-03-22 | — | — | CN | disclosed |
| WO-2022050529-A1 | COMPOSITION FOR DETECTING OR MEASURING ANALYTE | ㈜베르티스 | 2022-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11285103-B2 | Degradable hydrogel under physiological conditions | PTMS, TRHDE, PHYKPL | ADAM17 155/4885L3MBTL1 2049/4885CTSS 876/4885 |
| US-20250332271-A1 | PROGRAMMABLE SELECTIVE ACYLATION OF POLYOLS | PARG, PARN, NAAA | ADAM17 4411/4885L3MBTL1 1034/4885CTSS 4082/4885 |
| US-11512071-B2 | Decarboxylative cross-coupling and applications thereof | PPOX, DDO, DDC | ADAM17 2560/4885L3MBTL1 4559/4885CTSS 1614/4885 |
| US-20220332781-A1 | GLUCAGON-RECEPTOR SELECTIVE POLYPEPTIDES AND METHODS OF USE THEREOF | GLP1R, GIPR, GCGR | ADAM17 1442/4885L3MBTL1 2033/4885CTSS 2468/4885 |
| US-20260103499-A1 | BIOREVERSABLE PROMOIETIES FOR NITROGEN-CONTAINING AND HYDROXYL-CONTAINING DRUGS | CBR1, CBR3, SIGMAR1 | ADAM17 3408/4885L3MBTL1 2918/4885CTSS 1096/4885 |
| US-12466784-B2 | Analogs of pterostilbene amino acid bearing carbonates for treating a non-alcoholic fatty liver disease and nonalcoholic steatohepatitis | FABP1, GLS2, SLC1A5 | ADAM17 2138/4885L3MBTL1 2902/4885CTSS 1661/4885 |
| US-20220183990-A1 | PEPTIDE-FUNCTIONALIZED BIODEGRADABLE POLYMERS FOR EFFICIENT DELIVERY OF VARIOUS RNAS | RNASE1, SNRPE, HNRNPAB | ADAM17 575/4885L3MBTL1 74/4885CTSS 1230/4885 |
| US-12433845-B2 | Peptide-functionalized biodegradable polymers for efficient delivery of various RNAs | RNASE1, SNRPE, HNRNPAB | ADAM17 575/4885L3MBTL1 74/4885CTSS 1230/4885 |
| US-12528852-B2 | Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs | CBR1, CBR3, SIGMAR1 | ADAM17 3280/4885L3MBTL1 3490/4885CTSS 1283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.