SCHEMBL4294679

SCHEMBL4294679

CC(C)(C)OC(=O)N[C@H](Cc1cn(C(=O)OC(C)(C)C)c2ccccc12)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ADAM17 P78536 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.55
▸ CTSS P25774 3/20 0.50
▸ CTSK P43235 3/20 0.50
▸ ACE P12821 2/20 0.49
▸ CCKAR P32238 3/20 0.49
▸ CCKBR P32239 3/20 0.49
▸ OPRD1 P41143 3/20 0.49
▸ EPHX1 P07099 1/20 0.48
▸ SCN9A Q15858 1/20 0.47
▸ MAPK1 P28482 1/20 0.46
▸ CTSL P07711 2/20 0.46
▸ PPARA Q07869 2/20 0.45
▸ PPARG P37231 1/20 0.45
▸ PDE10A Q9Y233 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29401320 1.00 ADAM17 (0.58) ADAM17L3MBTL1CTSSCTSKACE
SCHEMBL10310207 1.00 ADAM17 (0.58) ADAM17L3MBTL1CTSSCTSKACE
SCHEMBL22804050 1.00 ADAM17 (0.58) ADAM17L3MBTL1CTSSCTSKACE
SCHEMBL29400491 1.00 ADAM17 (0.58) ADAM17L3MBTL1CTSSCTSKACE
SCHEMBL29401255 0.91 ADAM17 (0.58) ADAM17L3MBTL1CTSSCTSKCCKAR
SCHEMBL18002447 0.91 CTSS (0.50) ADAM17L3MBTL1CTSSCTSKACE
SCHEMBL29401597 0.91 ADAM17 (0.58) ADAM17L3MBTL1CTSSCTSKCCKAR
SCHEMBL21309886 0.90 L3MBTL1 (0.57) ADAM17L3MBTL1CTSSCTSKCCKAR
SCHEMBL29169598 0.90 L3MBTL1 (0.57) ADAM17L3MBTL1CTSSCTSKCCKAR
SCHEMBL22804106 0.90 ADAM17 (0.53) ADAM17L3MBTL1ACECCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP claimed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP disclosed
WO-2020252713-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF 浙江智达药业有限公司 2020-12-24 — — WO disclosed
US-20090305995-A1 AGONISTS AND ANTAGONISTS OF THE SOMATOSTATIN RECEPTOR NOVARTIS AG (CH) 2009-12-10 — — US disclosed
CN-101094861-A Agonists and antagonists of the somatostatin receptor NOVARTIS AG (CH) 2007-12-26 — — CN disclosed
EP-1814900-A1 AGONISTS AND ANTAGONISTS OF THE SOMATOSTATIN RECEPTOR Novartis AG (CH) 2007-08-08 — — EP disclosed
WO-2006053700-A1 AGONISTS AND ANTAGONISTS OF THE SOMATOSTATIN RECEPTOR NOVARTIS AG (CH) 2006-05-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090305995-A1 AGONISTS AND ANTAGONISTS OF THE SOMATOSTATIN RECEPTOR SSTR4, SSTR3, SSTR5 ADAM17 812/4885L3MBTL1 1870/4885CTSS 915/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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