Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021189 | 0.79 | RAB9A (0.41) | MAPTMEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL3040124 | 0.78 | RAB9A (0.41) | HSD17B10MAPTRAB9AKDM4EGAA | |
| SCHEMBL7863445 | 0.74 | RAB9A (0.45) | MAPTMEN1KMT2ASMN1; SMN2CYP1A2 | |
| SCHEMBL3039669 | 0.74 | RAB9A (0.42) | MAPTMEN1KMT2APDE10ASMN1; SMN2 | |
| SCHEMBL3021542 | 0.74 | RAB9A (0.39) | MAPTMEN1KMT2ASMN1; SMN2CYP2C9 | |
| SCHEMBL949224 | 0.74 | HSD17B10 (0.52) | HSD17B10PKMMAPTPOLBMEN1 | |
| SCHEMBL3027230 | 0.73 | HTR2A (0.37) | PKMMAPTPOLBMEN1KMT2A | |
| SCHEMBL3031734 | 0.71 | HRH2 (0.36) | HSD17B10PKMMAPTMEN1KMT2A | |
| SCHEMBL3034160 | 0.70 | TP53 (0.35) | ALDH1A1RAB9ATP53 | |
| SCHEMBL3028693 | 0.70 | PTPN11 (0.37) | KMT2ARAB9AKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096923-B1 | HETEROARYL AMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2014-01-22 | — | — | EP | disclosed |
| US-20130172549-A1 | Heteroaryl amide derivatives | H. LUNDBECK A/S (DK) | 2013-07-04 | — | — | US | disclosed |
| EP-2591675-A1 | Heteroaryl amide derivatives | H. Lundbeck A/S (DK) | 2013-05-15 | — | — | EP | disclosed |
| US-8431593-B2 | Heteroaryl amide derivatives | H. LUNDBECK A/S (DK) | 2013-04-30 | — | — | US | disclosed |
| US-20100216763-A1 | Heteroaryl Amide Derivatives | H. LUNDBECK A/S (DK) | 2010-08-26 | — | — | US | disclosed |
| EP-2096923-A2 | HETEROARYL AMIDE DERIVATIVES | H. Lundbeck A/S (DK) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008066789-A2 | HETEROARYL AMIDE DERIVATIVES | H. LUNDBECK A/S (DK) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100216763-A1 | Heteroaryl Amide Derivatives | HCAR2, PIGS, GPR52 | HSD17B10 1049/4885PKM 2938/4885MAPT 4321/4885 |
| US-20130172549-A1 | Heteroaryl amide derivatives | HCAR2, PIGS, GPR52 | HSD17B10 1049/4885PKM 2938/4885MAPT 4321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.