SCHEMBL30384263

SCHEMBL30384263

COc1ccc(/C=C/C(=O)c2ccc(O)cc2)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.88
MEN1 O00255 3/20 0.88
KMT2A Q03164 3/20 0.88
TNFRSF1A P19438 1/20 0.79
CTSL P07711 2/20 0.78
CA1 P00915 2/20 0.77
CA2 P00918 2/20 0.77
PDE4A P27815 1/20 0.75
PDE4B Q07343 1/20 0.75
PDE4C Q08493 1/20 0.75
PDE4D Q08499 1/20 0.75
MAPT P10636 3/20 0.73
LMNA P02545 2/20 0.73
ALDH1A1 P00352 2/20 0.73
NR1H4 Q96RI1 1/20 0.73
CYP1A1 P04798 1/20 0.72
CYP1A2 P05177 1/20 0.72
CYP2D6 P10635 1/20 0.72
CYP1B1 Q16678 1/20 0.72
KDM4E B2RXH2 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25199646 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL3440660 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL30383289 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL3440656 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL30415470 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL8977129 0.91 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL8977131 0.91 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL25197210 0.90 CTSL (0.76) ABCG2MEN1KMT2ACTSLCA1
SCHEMBL25184983 0.90 CTSL (0.76) ABCG2MEN1KMT2ACTSLCA1
SCHEMBL597849 0.90 CAPN1 (0.82) CTSLCA1CA2CAPN1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed