SCHEMBL25199646

SCHEMBL25199646

COc1ccc(/C=C\C(=O)c2ccc(O)cc2)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 4/20 0.88
MEN1 O00255 3/20 0.88
KMT2A Q03164 3/20 0.88
TNFRSF1A P19438 1/20 0.79
CTSL P07711 2/20 0.78
CA1 P00915 2/20 0.77
CA2 P00918 2/20 0.77
PDE4A P27815 1/20 0.75
PDE4B Q07343 1/20 0.75
PDE4C Q08493 1/20 0.75
PDE4D Q08499 1/20 0.75
MAPT P10636 3/20 0.73
LMNA P02545 2/20 0.73
ALDH1A1 P00352 2/20 0.73
NR1H4 Q96RI1 1/20 0.73
CYP1A1 P04798 1/20 0.72
CYP1A2 P05177 1/20 0.72
CYP2D6 P10635 1/20 0.72
CYP1B1 Q16678 1/20 0.72
KDM4E B2RXH2 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3440660 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL30383289 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL3440656 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL30415470 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL30384263 1.00 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL8977129 0.91 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL8977131 0.91 ABCG2 (0.88) ABCG2MEN1KMT2ATNFRSF1ACTSL
SCHEMBL25197210 0.90 CTSL (0.76) ABCG2MEN1KMT2ACTSLCA1
SCHEMBL25184983 0.90 CTSL (0.76) ABCG2MEN1KMT2ACTSLCA1
SCHEMBL597849 0.90 CAPN1 (0.82) CTSLCA1CA2CAPN1CTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders YEWSAVIN INC (US) 2026-01-15 US disclosed
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders YewSavin, Inc. (US) 2025-07-01 US disclosed
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-06-22 US disclosed
WO-2023086388-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2023-05-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260014100-A1 Compositions and Methods for Treating Bleeding and Bleeding Disorders SERPINC1, F2, F13B ABCG2 1606/4885MEN1 3367/4885KMT2A 2792/4885
US-20230190679-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MEN1 2457/4885KMT2A 3188/4885
US-12343317-B2 Compositions and methods for treating bleeding and bleeding disorders SERPINC1, SERPINE1, SERPINH1 ABCG2 3622/4885MEN1 2457/4885KMT2A 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.