Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.60 |
| ▸ | CSF1R | P07333 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.48 |
| ▸ | PRKACA | P17612 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.48 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038559 | 0.80 | CSF1R (0.39) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL27605278 | 0.76 | EGFR (0.68) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL27587642 | 0.76 | EGFR (0.68) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL27587640 | 0.76 | EGFR (0.68) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL8675772 | 0.75 | EGFR (0.56) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| Adenine SCHEMBL502575 | 0.69 | LMNA (0.63) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL30544086 | 0.69 | LRRK2 (0.67) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL9222313 | 0.69 | LMNA (0.79) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL6947463 | 0.68 | LRRK2 (0.56) | EGFRCSF1RHTTALDH1A1L3MBTL1 | |
| SCHEMBL75883 | 0.68 | NPSR1 (0.64) | HTTALDH1A1L3MBTL1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7749980-B2 | Non-nucleotide compositions and method for treating pain | INSPIRE PHARMACEUTICALS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20070123544-A1 | Non-nucleotide compositions and method for treating pain | INSPIRE PHARMACEUTICALS, INC. | 2007-05-31 | — | — | US | disclosed |
| EP-0540854-B1 | Preparation for promoting hair growth | SANSHO SEIYAKU KK (JP) | 1998-01-21 | — | — | EP | disclosed |
| US-5656264-A | ADMINISTERING TO THE SCALP OF THE MALE A PREPERATION CONSITING OF 6-BENZYLAMINOPURINE | SANSYO SEIYAKU CO., LTD. (JP) | 1997-08-12 | — | — | US | disclosed |
| EP-0540854-A2 | Preparation for promoting hair growth | Sansho Seiyaku Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123544-A1 | Non-nucleotide compositions and method for treating pain | P2RX3, P2RX5, P2RX1 | EGFR 3034/4885CSF1R 2269/4885HTT 3454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.