Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.47 |
| ▸ | UBE2M | P61081 | 1/20 | 0.46 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 2/20 | 0.45 |
| ▸ | CA9 | Q16790 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CCR2 | P41597 | 2/20 | 0.45 |
| ▸ | CCR3 | P51677 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3043043 | 0.97 | MEN1 (0.48) | TACR1MCHR1UBE2MDCUN1D1CA1 | |
| SCHEMBL3041690 | 0.95 | CCR2 (0.46) | TACR1MCHR1UBE2MDCUN1D1CA1 | |
| SCHEMBL3034250 | 0.89 | FAAH (0.44) | MCHR1SMN1; SMN2ALDH1A1TSHRCCR2 | |
| SCHEMBL14221707 | 0.87 | MAPT (0.48) | MCHR1SMN1; SMN2ALDH1A1MEN1TSHR | |
| SCHEMBL3038625 | 0.86 | ALDH1A1 (0.53) | TACR1MCHR1UBE2MDCUN1D1LMNA | |
| SCHEMBL3033257 | 0.86 | ALDH1A1 (0.48) | TACR1MCHR1CA1CA2CA7 | |
| SCHEMBL3778720 | 0.85 | PARP1 (0.51) | MCHR1TSHRKMT2ACCR2 | |
| SCHEMBL13222974 | 0.85 | CCR2 (0.47) | TACR1SMN1; SMN2ALDH1A1TSHRCCR2 | |
| SCHEMBL14221740 | 0.85 | CCR2 (0.43) | SMN1; SMN2ALDH1A1TSHRCCR2 | |
| SCHEMBL3038611 | 0.84 | FAAH (0.49) | TACR1MCHR1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | claimed |
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | EPIX DELAWARE, INC. (US) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210633-A1 | CARBOXAMIDE COMPOUNDS AND THEIR USE | CCR2, CCR1, CCR5 | TACR1 539/4885MCHR1 325/4885UBE2M 4733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.