Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | HAT1 | O14929 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17850497 | 0.84 | GPR84 (0.51) | GPR84ALDH1A1NR4A2SLC6A4POLB | |
| SCHEMBL30684580 | 0.84 | GPR84 (0.51) | GPR84ALDH1A1NR4A2SLC6A4POLB | |
| SCHEMBL21596979 | 0.83 | GPR84 (0.50) | GPR84ALDH1A1NR4A2SLC6A4POLB | |
| SCHEMBL5731140 | 0.83 | GPR84 (0.50) | GPR84ALDH1A1NR4A2SLC6A4POLB | |
| SCHEMBL30286607 | 0.81 | IMPDH2 (0.45) | ALDH1A1POLBDUSP3PTPN5PTPN11 | |
| SCHEMBL28316381 | 0.79 | HTR2A (0.53) | ALDH1A1NR4A2POLBDUSP3PTPN5 | |
| SCHEMBL31734429 | 0.79 | TDO2 (0.60) | GPR84IDO1TDO2HTR2A | |
| SCHEMBL28799587 | 0.77 | ASH1L (0.43) | GPR84MMP2CA12CA1CA2 | |
| SCHEMBL21545957 | 0.76 | CES1 (0.47) | GPR84ALDH1A1NR4A2 | |
| SCHEMBL29561166 | 0.76 | CES1 (0.47) | GPR84ALDH1A1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4298092-B1 | NOVEL PYRIMIDIN-2-YL SULFONAMIDE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2025-11-26 | — | — | EP | claimed |
| CN-116036078-A | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2023-05-02 | — | — | CN | disclosed |