Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 3/20 | 0.45 |
| ▸ | TDO2 | P48775 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31734429 | 0.81 | TDO2 (0.60) | TDO2HTR2A | |
| SCHEMBL28316381 | 0.81 | HTR2A (0.53) | TDO2DUSP3PTPN5PTPN11CA12 | |
| SCHEMBL30388498 | 0.81 | GPR84 (0.54) | TDO2PARP1DUSP3PTPN5PTPN11 | |
| SCHEMBL22778025 | 0.80 | IMPDH2 (0.41) | IMPDH2TDO2PARP1ASH1LCLK1 | |
| SCHEMBL6764140 | 0.79 | SLC6A2 (0.49) | IMPDH2HTR2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL28799587 | 0.78 | ASH1L (0.43) | TDO2PARP1ASH1LMMP2CA12 | |
| SCHEMBL30286798 | 0.76 | PKM (0.55) | PARP1CLK1CDK5CDK5R1CA12 | |
| SCHEMBL32896 | 0.76 | CYP3A4 (0.48) | IMPDH2CA1CA2CA9TDP1 | |
| SCHEMBL31734414 | 0.74 | CA2 (0.46) | TDO2CA2HTR2AMAPT | |
| SCHEMBL5269899 | 0.73 | IMPDH2 (0.50) | IMPDH2PARP1ASH1LCLK1CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110121499-B | (aza) indole-, benzothiophene-and benzofuran-3-sulfonamides | 优时比制药有限公司 | 2022-12-20 | — | — | CN | disclosed |