Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 2/20 | 0.42 |
| ▸ | PRKCA | P17252 | 1/20 | 0.42 |
| ▸ | FGF1 | P05230 | 1/20 | 0.41 |
| ▸ | FGF2 | P09038 | 1/20 | 0.41 |
| ▸ | VEGFA | P15692 | 1/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | HRAS | P01112 | 1/20 | 0.37 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.37 |
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30891388 | 0.91 | TGM2 (0.44) | LGALS8MMP13MAOBTGM2HTT | |
| SCHEMBL29880337 | 0.88 | MMP13 (0.46) | LGALS8PRKCAFGF1FGF2VEGFA | |
| SCHEMBL30891369 | 0.88 | MMP13 (0.46) | LGALS8PRKCAFGF1FGF2VEGFA | |
| SCHEMBL30891312 | 0.88 | MMP13 (0.46) | LGALS8PRKCAFGF1FGF2VEGFA | |
| SCHEMBL30891306 | 0.87 | MMP13 (0.47) | LGALS8PRKCAFGF1FGF2VEGFA | |
| SCHEMBL30891501 | 0.86 | MMP13 (0.42) | LGALS8PRKCAFGF1FGF2VEGFA | |
| SCHEMBL20511211 | 0.85 | CD209 (0.48) | LGALS8PRKCAFGF1FGF2VEGFA | |
| SCHEMBL12094119 | 0.84 | LGALS3 (0.54) | LGALS8FGF1FGF2VEGFAHPSE | |
| SCHEMBL19036050 | 0.84 | LGALS3 (0.54) | LGALS8FGF1FGF2VEGFAHPSE | |
| SCHEMBL12094113 | 0.84 | LGALS3 (0.54) | LGALS8FGF1FGF2VEGFAHPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436610-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | Merck Sharp & Dohme LLC (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023091441-A1 | GLUCOSE-RESPONSIVE INSULIN CONJUGATES COMPRISING A TETRA-VALENT SUGAR CLUSTER FOR TREATMENT OF DIABETES | MERCK SHARP & DOHME LLC (US) | 2023-05-25 | — | — | WO | disclosed |