Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22987816 | 1.00 | ADORA3 (0.43) | ADORA3ADORA2AADORA1HSP90AB1NR4A2 | |
| SCHEMBL22988254 | 0.88 | ADORA3 (0.42) | ADORA3ADORA2AADORA1ALDH1A1ADORA2B | |
| SCHEMBL22987632 | 0.86 | ADORA3 (0.40) | ADORA3ADORA2AADORA1ALDH1A1 | |
| SCHEMBL22988101 | 0.85 | HSP90AB1 (0.42) | ADORA3ADORA2AADORA1HSP90AB1NR4A2 | |
| SCHEMBL30392927 | 0.85 | HSP90AB1 (0.42) | ADORA3ADORA2AADORA1HSP90AB1NR4A2 | |
| SCHEMBL22979975 | 0.79 | HSP90AB1 (0.42) | ADORA3ADORA2AADORA1HSP90AB1NR4A2 | |
| SCHEMBL29645906 | 0.78 | ADORA3 (0.36) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL22987714 | 0.77 | XDH (0.47) | ADORA3ALDH1A1XDH | |
| SCHEMBL31149946 | 0.76 | ADORA3 (0.35) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL22987758 | 0.74 | ALDH1A1 (0.40) | ADORA3ADORA2AADORA1HSP90AB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230113037-A1 | [1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-5-AMINES | AHR, HRH4, HRH1 | ADORA3 34/4885ADORA2A 103/4885ADORA1 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.