Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306413 | 0.88 | KIF11 (0.44) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL30393232 | 0.85 | CYP11B1 (0.41) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL3315684 | 0.85 | HDAC6 (0.44) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL3310395 | 0.85 | KIF11 (0.43) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL4596531 | 0.82 | GRIN1 (0.46) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL3311164 | 0.81 | S1PR1 (0.46) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL3306832 | 0.80 | MET (0.47) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL3309660 | 0.80 | KIF11 (0.45) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL3306622 | 0.80 | CYP11B1 (0.46) | KIF11MAPTHDAC6HDAC1CYP1A2 | |
| SCHEMBL13273166 | 0.79 | CYP11B2 (0.60) | KIF11HDAC6HDAC1CYP1A2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023059605-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND THEIR USE IN TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2023-04-13 | — | — | WO | disclosed |