Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 2/20 | 0.72 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.44 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.44 |
| ▸ | ULK1 | O75385 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | AXL | P30530 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20536131 | 1.00 | RHEB (0.72) | RHEBXDHGRIN1GAANR4A2 | |
| SCHEMBL20536478 | 0.86 | RHEB (0.69) | RHEBXDHGRIN1NR4A2EIF4A3 | |
| SCHEMBL20536585 | 0.84 | RHEB (1.00) | RHEBGRIN1GAAEIF4A3FTO | |
| SCHEMBL20536129 | 0.82 | XDH (0.60) | RHEBXDHGRIN1GAANR4A2 | |
| SCHEMBL30395343 | 0.82 | XDH (0.60) | RHEBXDHGRIN1GAANR4A2 | |
| SCHEMBL20536070 | 0.80 | RHEB (0.46) | RHEBXDHGRIN1GAANR4A2 | |
| SCHEMBL9433015 | 0.80 | GRIN1 (0.66) | RHEBGRIN1NR4A2EIF4A3ULK1 | |
| SCHEMBL5568273 | 0.79 | FLT3 (0.59) | GAANR4A2ULK1KIF11FLT3 | |
| SCHEMBL26372677 | 0.79 | ULK1 (0.48) | RHEBXDHGRIN1NR4A2EIF4A3 | |
| SCHEMBL30396705 | 0.78 | FLT3 (0.47) | RHEBXDHULK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4165037-A1 | ANTI-VIRAL COMPOUNDS FOR TREATING CORONAVIRUS, PICORNAVIRUS, AND NOROVIRUS INFECTIONS | Aligos Therapeutics, Inc. (US) | 2023-04-19 | — | — | EP | disclosed |