Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30397831 | 0.84 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL30398306 | 0.83 | GRM2 (0.38) | GRM2MAPK1 | |
| SCHEMBL30396233 | 0.83 | GRM2 (0.38) | GRM2MAPK1 | |
| SCHEMBL30397394 | 0.79 | GRM2 (0.37) | ALDH1A1MEN1KMT2AGRM2 | |
| SCHEMBL25526353 | 0.73 | GRM2 (0.43) | GRM2MAPK1 | |
| SCHEMBL30397943 | 0.72 | MAPK13 (0.41) | GRM2 | |
| SCHEMBL30397669 | 0.72 | MAPK13 (0.41) | GRM2 | |
| SCHEMBL25523929 | 0.71 | GRM2 (0.40) | SMN1; SMN2ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL25521381 | 0.71 | GRM2 (0.40) | GRM2MAPK1 | |
| SCHEMBL25522679 | 0.71 | GRM2 (0.40) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |