SCHEMBL30398232

SCHEMBL30398232

O=c1[nH]c2c(Br)cc(Br)cc2c(=O)o1

nearest known ligand 0.41

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.41
F2 P00734 1/20 0.39
CFD P00746 1/20 0.39
NQO1 P15559 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
POLB P06746 1/20 0.38
MAOB P27338 4/20 0.38
MAOA P21397 3/20 0.38
MEN1 O00255 1/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
ESR2 Q92731 3/20 0.34
ESR1 P03372 2/20 0.34
GPR35 Q9HC97 3/20 0.33
PTPN1 P18031 1/20 0.33
MCL1 Q07820 1/20 0.32
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL639250 1.00 RAB9A (0.41) RAB9AF2CFDNQO1ALDH1A1
SCHEMBL21751078 0.82 ALDH1A1 (0.47) F2CFDALDH1A1MAPTPOLB
SCHEMBL14698281 0.82 F2 (0.37) F2CFDALDH1A1MAOBMAOA
SCHEMBL3208633 0.82 GSK3B (0.38) RAB9AF2CFDNQO1MAOB
SCHEMBL14698260 0.82 MAOA (0.39) RAB9AF2CFDNQO1ALDH1A1
SCHEMBL14698286 0.78 KDM4E (0.35) RAB9AF2CFDALDH1A1POLB
SCHEMBL20350863 0.78 MAOB (0.38) F2CFDALDH1A1MAPTMAOB
SCHEMBL14698261 0.78 MAOA (0.38) F2CFDMAOBMAOAGRM5
SCHEMBL10780521 0.77 GRM5 (0.38) ALDH1A1MAPTPOLBGPR35MCL1
SCHEMBL6739074 0.74 F2 (0.52) F2CFDMAOBMAOAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117625288-A Lubricating oil composition special for unmanned aerial vehicle 中国石油化工股份有限公司 2024-03-01 CN claimed
CN-117625250-A Scale inhibition composition and application thereof 中国石油化工股份有限公司 2024-03-01 CN claimed
CN-117625272-A Gear oil composition 中国石油化工股份有限公司 2024-03-01 CN claimed
CN-116063589-A Soot ashless dispersant, and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN claimed
CN-117625288-A Lubricating oil composition special for unmanned aerial vehicle 中国石油化工股份有限公司 2024-03-01 CN disclosed
CN-117625250-A Scale inhibition composition and application thereof 中国石油化工股份有限公司 2024-03-01 CN disclosed
CN-117625272-A Gear oil composition 中国石油化工股份有限公司 2024-03-01 CN disclosed
CN-116063589-A Soot ashless dispersant, and preparation method and application thereof 中国石油化工股份有限公司 2023-05-05 CN disclosed