SCHEMBL14698286

SCHEMBL14698286

O=c1[nH]c2c(C(F)(F)F)cc(Br)cc2c(=O)o1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.35
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
POLB P06746 1/20 0.35
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
KMT2A Q03164 1/20 0.35
F2 P00734 1/20 0.34
CFD P00746 1/20 0.34
MAOA P21397 3/20 0.34
MAOB P27338 3/20 0.34
NOTUM Q6P988 1/20 0.34
RAB9A P51151 1/20 0.33
C1R P00736 1/20 0.32
HCAR1 Q9BXC0 1/20 0.32
AR P10275 2/20 0.31
EPRS1 P07814 1/20 0.31
ELANE P08246 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14698509 0.81 KDM4E (0.35) KDM4ESMN1; SMN2MEN1ALDH1A1LMNA
SCHEMBL639250 0.78 RAB9A (0.41) MEN1ALDH1A1POLBKMT2AF2
SCHEMBL30398232 0.78 RAB9A (0.41) MEN1ALDH1A1POLBKMT2AF2
SCHEMBL14698260 0.76 MAOA (0.39) KDM4EALDH1A1LMNAF2CFD
SCHEMBL3208633 0.76 GSK3B (0.38) LMNAHPGDF2CFDMAOA
SCHEMBL14698261 0.75 MAOA (0.38) KDM4EF2CFDMAOAMAOB
SCHEMBL28329316 0.74 SMN1; SMN2 (0.54) KDM4ESMN1; SMN2MEN1ALDH1A1LMNA
SCHEMBL20350863 0.72 MAOB (0.38) ALDH1A1HPGDF2CFDMAOA
SCHEMBL14698522 0.69 MAOA (0.40) KDM4EF2CFDMAOAMAOB
SCHEMBL2323041 0.67 ALDH1A1 (0.54) KDM4ESMN1; SMN2MEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556141-B2 Process for preparing N-substituted 1H-pyrazole-5-carboxylate compounds and derivatives thereof BASF SE (DE) 2017-01-31 US disclosed
US-9282741-B2 Aniline type compounds BASF SE (DE) 2016-03-15 US disclosed
EP-2782910-B1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2016-02-03 EP disclosed
EP-2742037-B1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2015-10-14 EP disclosed
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150250174-A1 USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS BASF SE (DE) 2015-09-10 US disclosed
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-09-10 US disclosed
US-20150250172-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS BASF SE (DE) 2015-09-10 US disclosed
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2015-08-27 US disclosed
EP-2903442-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2015-08-12 EP disclosed
WO-2014053395-A1 USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053403-A1 METHOD OF CONTROLLING INSECTICIDE RESISTANT INSECTS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053396-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053404-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS BASF SE (DE) 2014-04-10 WO disclosed
WO-2014053407-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-04-10 WO disclosed
WO-2013076092-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBOXYLATE COMPOUNDS AND DERIVATIVES THEREOF BASF SE (DE) 2013-05-30 WO disclosed
WO-2013024010-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024009-A1 N-THIO-ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024007-A1 PROCESS FOR PREPARING N-SUBSTITUTED 1H-PYRAZOLE-5-CARBONYLCHLORIDE COMPOUNDS BASF SE (DE) 2013-02-21 WO disclosed
WO-2013024008-A1 ANILINE TYPE COMPOUNDS BASF SE (DE) 2013-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150250174-A1 USE OF N-THIO-ANTHRANILAMIDE COMPOUNDS ON CULTIVATED PLANTS NAT1, TST, NIT2 KDM4E 1944/4885SMN1; SMN2 4588/4885MEN1 3978/4885
US-20150250173-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS AADAC, ARSA, SIRT7 KDM4E 1796/4885SMN1; SMN2 2331/4885MEN1 1682/4885
US-20150250175-A1 PESTICIDALLY ACTIVE MIXTURES COMPRISING ANTHRANILAMIDE COMPOUNDS MCU, AGK, MLYCD KDM4E 2270/4885SMN1; SMN2 4665/4885MEN1 1267/4885
US-20150250172-A1 USE OF ANTHRANILAMIDE COMPOUNDS IN SOIL AND SEED TREATMENT APPLICATION METHODS HRH3, DDT, ANTXR2 KDM4E 563/4885SMN1; SMN2 3894/4885MEN1 2504/4885
US-20150237858-A1 METHOD OF CONTROLLING RYANODINE-MODULATOR INSECTICIDE RESISTANT INSECTS RYR2, RYR1, CRY1 KDM4E 209/4885SMN1; SMN2 4415/4885MEN1 4195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.