Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | HPGD | P15428 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | CASP3 | P42574 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.67 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.67 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | MGAM | O43451 | 4/20 | 0.59 |
| ▸ | MAOA | P21397 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025501 | 1.00 | PTGS2 (0.69) | PTGS2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL30786757 | 0.83 | MGAM (0.84) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL20356594 | 0.83 | MAOA (0.67) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL15918267 | 0.83 | MGAM (0.84) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL30346193 | 0.83 | MAOA (0.67) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL30435802 | 0.82 | MAOA (0.68) | PTGS2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL14252988 | 0.82 | ALDH1A1 (0.65) | PTGS2KDM4EALDH1A1HPGDMAPT | |
| SCHEMBL6907196 | 0.82 | MGAM (0.73) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL30346426 | 0.82 | MGAM (0.73) | KDM4EALDH1A1HPGDMAPTNPC1 | |
| SCHEMBL2161251 | 0.81 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178331-B | Antidiabetic xanthone compound 2-hydroxyxanthone, preparation method, pharmaceutical composition and application thereof | 中日友好医院(中日友好临床医学研究所) | 2023-07-07 | — | — | CN | disclosed |
| CN-116178331-A | Antidiabetic xanthone compound 2-hydroxyxanthone, preparation method, pharmaceutical composition and application thereof | 中日友好医院(中日友好临床医学研究所) | 2023-05-30 | — | — | CN | disclosed |