Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18395133 | 1.00 | POLB (0.48) | POLBTP53OPRK1KMOTHRB | |
| SCHEMBL18412768 | 0.87 | ALDH1A1 (0.51) | TP53OPRK1THRBPIK3CAKDM4E | |
| SCHEMBL24611900 | 0.87 | AURKA (0.48) | TP53OPRK1THRBPIK3CAKDM4E | |
| SCHEMBL30402068 | 0.87 | AURKA (0.48) | TP53OPRK1THRBPIK3CAKDM4E | |
| SCHEMBL18394825 | 0.83 | TP53 (0.49) | TP53OPRK1THRBKDM4EALDH1A1 | |
| SCHEMBL17478763 | 0.82 | OPRK1 (0.60) | POLBTP53OPRK1KMOPIK3CA | |
| SCHEMBL17478716 | 0.82 | PRKAB2 (0.50) | POLBTP53OPRK1KMOTHRB | |
| SCHEMBL24611941 | 0.82 | POLB (0.48) | POLBTP53OPRK1KMOPIK3CA | |
| SCHEMBL18394680 | 0.82 | SCN10A (0.50) | KDM4EALDH1A1 | |
| SCHEMBL18394397 | 0.80 | ALOX15 (0.55) | POLBTP53OPRK1PIK3CAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |