Acetic Acid

Acetic Acid

SCHEMBL30401693

CC(=O)O.CC(=O)O.O=C(O)CNCC(=O)O

nearest known ligand 0.48

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTH P32929 1/20 0.48
FFAR3 O14843 3/20 0.47
LCK P06239 1/20 0.47
FYN P06241 1/20 0.47
LMNA P02545 4/20 0.45
SLC15A2 Q16348 1/20 0.45
EGLN1 Q9GZT9 5/20 0.43
KDM4E B2RXH2 2/20 0.43
KDM5C P41229 2/20 0.43
PHF8 Q9UPP1 2/20 0.43
KDM2A Q9Y2K7 2/20 0.43
KDM6B O15054 1/20 0.43
LDHA P00338 1/20 0.41
SRR Q9GZT4 1/20 0.41
ALKBH5 Q6P6C2 1/20 0.41
SUCNR1 Q9BXA5 1/20 0.41
HDAC3 O15379 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL31437203 1.00 CTH (0.48) CTHFFAR3LCKFYNLMNA
SCHEMBL4816014 0.89 LMNA (0.50) CTHFFAR3LMNAEGLN1KDM4E
SCHEMBL27023 0.89
SCHEMBL597185 0.88
Acetamide SCHEMBL15006561 0.88 LMNA (0.47) CTHFFAR3LMNASLC15A2EGLN1
SCHEMBL3464176 0.86 LMNA (0.47) CTHFFAR3LMNAEGLN1KDM4E
SCHEMBL667660 0.86 LMNA (0.47) CTHFFAR3LMNAEGLN1KDM4E
Ammonia Solution, Strong SCHEMBL7262621 0.86 LMNA (0.47) CTHFFAR3LMNAEGLN1KDM4E
SCHEMBL9393647 0.86 LMNA (0.47) CTHFFAR3LMNAEGLN1KDM4E
Ammonia Solution, Strong SCHEMBL7262619 0.86 LMNA (0.47) CTHFFAR3LMNAEGLN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178187-B Method for preparing methyl glycine-N, N-diacetic acid tri-alkali metal salt 万华化学集团股份有限公司 2024-12-03 CN disclosed
CN-116178187-A Method for preparing methyl glycine-N, N-diacetic acid tri-alkali metal salt 万华化学集团股份有限公司 2023-05-30 CN disclosed