Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.64 |
| ▸ | CTSK | P43235 | 3/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | BACE1 | P56817 | 13/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15113474 | 0.90 | CTSS (0.60) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL22648530 | 0.89 | CTSS (0.60) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL10144064 | 0.86 | CTSS (0.57) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL11698208 | 0.84 | CTSS (0.55) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL20628143 | 0.84 | BACE1 (0.52) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL29576064 | 0.84 | BACE1 (0.52) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL10727619 | 0.84 | CTSS (0.62) | CTSSCTSKTSHRBACE1BACE2 | |
| SCHEMBL478905 | 0.83 | CTSS (0.68) | CTSSCTSKTSHRCA2 | |
| SCHEMBL352156 | 0.83 | CTSS (0.68) | CTSSCTSKTSHRCA2 | |
| SCHEMBL4395744 | 0.83 | CTSS (0.68) | CTSSCTSKTSHRCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116077686-A | Enzyme-cleavable Linker and application thereof | 苏州智核生物医药科技有限公司 | 2023-05-09 | — | — | CN | disclosed |