Sugi Predict

Sugi Predict / Compounds / SCHEMBL352156

SCHEMBL352156

SCHEMBL352156

CSCC[C@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.68

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ CTSS P25774 4/20 0.68
▸ CTSK P43235 4/20 0.68
▸ TSHR P16473 2/20 0.54
▸ CA2 P00918 1/20 0.49
▸ LMNA P02545 1/20 0.48
▸ PPARG P37231 3/20 0.47
▸ PPARA Q07869 3/20 0.47
▸ KLK7 P49862 1/20 0.47
▸ EPHX2 P34913 1/20 0.47
▸ USP2 O75604 1/20 0.46
▸ MAPK1 P28482 1/20 0.46
▸ PPARD Q03181 2/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ KLK5 Q9Y337 1/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL478905 1.00 CTSS (0.68) CTSSCTSKTSHRCA2LMNA
SCHEMBL4395744 1.00 CTSS (0.68) CTSSCTSKTSHRCA2LMNA
SCHEMBL1486229 1.00 CTSS (0.68) CTSSCTSKTSHRCA2LMNA
Methanesulfonamide SCHEMBL6898028 0.92 CTSS (0.60) CTSSCTSKTSHRCA2LMNA
Methanesulfonamide SCHEMBL6777577 0.92 CTSS (0.60) CTSSCTSKTSHRCA2LMNA
SCHEMBL2118282 0.90 CTSK (0.56) CTSSCTSKTSHRCA2PPARG
SCHEMBL2118283 0.90 CTSK (0.56) CTSSCTSKTSHRCA2PPARG
SCHEMBL7874195 0.89 CTSS (0.57) CTSSCTSKTSHRCA2LMNA
SCHEMBL7874192 0.89 CTSS (0.57) CTSSCTSKTSHRCA2LMNA
SCHEMBL16715127 0.89 CTSK (0.56) CTSSCTSKTSHRCA2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 854 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120136948-A Cycloastragal derivative with activity of resisting methicillin-resistant staphylococcus aureus and preparation method thereof 山西医科大学 2025-06-13 — — CN claimed
CN-119528812-B Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-06-03 — — CN claimed
CN-119775353-A Short peptide compound and preparation method thereof, cosmetic composition and application 常州市智态生创科技有限公司 2025-04-08 — — CN claimed
CN-119528812-A Double amino acid-genipin derivative and preparation method and application thereof 广东工业大学 2025-02-28 — — CN claimed
CN-119118908-A Rhein nitroxide free radical derivative and synthetic method and application thereof 甘肃中医药大学 2024-12-13 — — CN claimed
CN-116425649-B Amino acid-curcumin derivative and preparation method and application thereof 八叶草生物科技(三明)有限公司 2024-09-17 — — CN claimed
CN-116987148-B Synthesis process of acetyl hexapeptide-8 山东济肽生物科技有限公司 2024-07-05 — — CN claimed
CN-118085005-A 18 Beta-glycyrrhetinic acid derivative and preparation method and application thereof 石河子大学 2024-05-28 — — CN claimed
CN-111825742-B Polypeptide solid phase synthesis of CTPA as special coupling agent for amino acid ionic liquid 陈铭 2024-01-30 — — CN claimed
CN-117304131-A Alpha-carbonyl alkenyl ester compound, and preparation method and application thereof 广州医科大学 2023-12-29 — — CN claimed
US-6951946-B2 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates LEXICON PHARMACEUTICALS, INC. (US) 2005-10-04 — — US claimed
US-20050154211-A1 Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates KOLB HARTMUTH C (US) 2005-07-14 — — US claimed
US-20050020650-A1 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof DONG WHA PHARM. CO., LTD. (KR) 2005-01-27 — — US claimed
EP-1451163-A4 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARM IND CO LTD (KR) 2005-01-26 — — EP claimed
EP-1451163-A1 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARMACEUTICAL INDUSTRIAL CO. LTD. (KR) 2004-09-01 — — EP claimed
US-20040019215-A1 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates LEXICON PHARMACEUTICALS, INC. 2004-01-29 — — US claimed
WO-2003040113-A1 3-AMIDO-1,2-BENZOISOXAZOLE DERIVATIVES, PROCESS FOR PREPARATION, AND USE THEREOF DONG WHA PHARM. IND. CO., LTD. (KR) 2003-05-15 — — WO claimed
US-5763647-A THROMBOXANE A2 RECEPTOR ANTAGONISTS SHIONOGI & CO., LTD. (JP) 1998-06-09 — — US claimed
EP-0452000-B1 Preparation of optically active norbornyl amine derivatives SHIONOGI & CO (JP) 1995-10-18 — — EP claimed
EP-0452000-A2 Preparation of optically active norbornyl amine derivatives SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. (JP) 1991-10-16 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020650-A1 3-amido-1,2-benzoisoxazole derivatives, process for preparation, and use thereof LTB4R, FPR1, LTB4R2 CTSS 518/4885CTSK 461/4885TSHR 816/4885
US-20050154211-A1 Large scale synthesis of 1,2,4- and 1,3,4- oxadiazole carboxylates OXA1L, ODC1, CYP4B1 CTSS 2627/4885CTSK 2356/4885TSHR 4013/4885
US-20040019215-A1 Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylates OXA1L, ODC1, CYP4B1 CTSS 2627/4885CTSK 2356/4885TSHR 4013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.