Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.68 |
| ▸ | CTSK | P43235 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL352156 | 1.00 | CTSS (0.68) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL4395744 | 1.00 | CTSS (0.68) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL1486229 | 1.00 | CTSS (0.68) | CTSSCTSKTSHRCA2LMNA | |
| Methanesulfonamide SCHEMBL6898028 | 0.92 | CTSS (0.60) | CTSSCTSKTSHRCA2LMNA | |
| Methanesulfonamide SCHEMBL6777577 | 0.92 | CTSS (0.60) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL2118282 | 0.90 | CTSK (0.56) | CTSSCTSKTSHRCA2PPARG | |
| SCHEMBL2118283 | 0.90 | CTSK (0.56) | CTSSCTSKTSHRCA2PPARG | |
| SCHEMBL7874195 | 0.89 | CTSS (0.57) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL7874192 | 0.89 | CTSS (0.57) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL16715127 | 0.89 | CTSK (0.56) | CTSSCTSKTSHRCA2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000520-B2 | B-vitamin and amino acid conjugates ofnicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof | ChromaDex Inc. (US) | 2018-06-19 | — | — | US | claimed |
| CN-107708432-A | Rumen bypass animal feed composition and preparation method thereof | 拜内梅尔克公司 | 2018-02-16 | — | — | CN | claimed |
| US-20170267709-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OFNICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | ChromaDex Inc. (US) | 2017-09-21 | — | — | US | claimed |
| CN-103421087-A | Liquid-phase synthesizing method for polypeptide | SHANGHAI BAJIAYI PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-12-04 | — | — | CN | claimed |
| CN-102775591-A | Preparation method of tetraamino-terminated glycolide-lactide telechelic copolymer | UNIV HEBEI SCIENCE & TECH | 2012-11-14 | — | — | CN | claimed |
| CN-1241935-C | Liquid phase sgnthesis method of thymus pentapeptide | UNIV LANZHOU (CN) | 2006-02-15 | — | — | CN | claimed |
| CN-1634975-A | Process for preparing 2,4-synthetic antigen with added spacing arms | UNIV TSINGHUA (CN) | 2005-07-06 | — | — | CN | claimed |
| CN-1513872-A | Liquid phase sgnthesis method of thymus pentapeptide | 兰州大学 | 2004-07-21 | — | — | CN | claimed |
| US-12625431-B2 | EUV resist underlayer film-forming composition | NISSAN CHEMICAL CORPORATION (JP) | 2026-05-12 | — | — | US | disclosed |
| US-12617782-B2 | Pyridazinones as PARP7 inhibitors | RIBON THERAPEUTICS, INC. (US) | 2026-05-05 | — | — | US | disclosed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-12516063-B2 | Substituted 7-(methylamino)pyrazolo[1,5-a]pyrimidine-3-carboxamide derivatives for treating autoimmune diseases | ELI LILLY AND COMPANY (US) | 2026-01-06 | — | — | US | disclosed |
| EP-3966226-B1 | MASP INHIBITORY COMPOUNDS AND USES THEREOF | BAYER AG (DE) | 2025-12-24 | — | — | EP | disclosed |
| US-12503491-B2 | MASP inhibitory compounds and uses thereof | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-23 | — | — | US | disclosed |
| US-5430052-A | Protective effect against myocardial disorders caused by calcium ion overload; antiischemic agents; remedy for heart failure, angina pectoris | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| CN-1066070-A | Promote the new benzo-fused lactams that tethelin discharges | MERCK & CO INC (US) | 1992-11-11 | — | — | CN | disclosed |
| EP-0467856-A2 | Aminoalkanesulfonic acid derivatives and pharmaceutical compositions for use in preventing or treating heart diseases | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1992-01-22 | — | — | EP | disclosed |
| EP-0376040-A2 | N-phosphinyl di-and tripeptides as renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |
| EP-0186977-A2 | Renin-inhibitory dipeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1986-07-09 | — | — | EP | disclosed |
| US-3968226-A | 3-Heterocyclic thiomethylcephalosporins as antibacterial agents | SMITHKLINE CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12503491-B2 | MASP inhibitory compounds and uses thereof | MASP2, SERPINB1, SPINT2 | CTSS 138/4885CTSK 149/4885TSHR 3032/4885 |
| US-10000520-B2 | B-vitamin and amino acid conjugates ofnicotinoyl ribosides and reduced nicotinoyl ribosides, derivatives thereof, and methods of preparation thereof | NAMPT, NAPRT, NNMT | CTSS 4478/4885CTSK 4555/4885TSHR 833/4885 |
| US-12625431-B2 | EUV resist underlayer film-forming composition | EEF1A1, ARF1, EMG1 | CTSS 4528/4885CTSK 3728/4885TSHR 3840/4885 |
| US-12617782-B2 | Pyridazinones as PARP7 inhibitors | PARP3, PARP2, PARP1 | CTSS 1086/4885CTSK 1225/4885TSHR 371/4885 |
| US-20170267709-A1 | B-VITAMIN AND AMINO ACID CONJUGATES OFNICOTINOYL RIBOSIDES AND REDUCED NICOTINOYL RIBOSIDES, DERIVATIVES THEREOF, AND METHODS OF PREPARATION THEREOF | NAMPT, NAPRT, NNMT | CTSS 4478/4885CTSK 4555/4885TSHR 833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.