Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.68 |
| ▸ | CTSK | P43235 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.47 |
| ▸ | KLK7 | P49862 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL478905 | 1.00 | CTSS (0.68) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL352156 | 1.00 | CTSS (0.68) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL1486229 | 1.00 | CTSS (0.68) | CTSSCTSKTSHRCA2LMNA | |
| Methanesulfonamide SCHEMBL6898028 | 0.92 | CTSS (0.60) | CTSSCTSKTSHRCA2LMNA | |
| Methanesulfonamide SCHEMBL6777577 | 0.92 | CTSS (0.60) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL2118282 | 0.90 | CTSK (0.56) | CTSSCTSKTSHRCA2PPARG | |
| SCHEMBL2118283 | 0.90 | CTSK (0.56) | CTSSCTSKTSHRCA2PPARG | |
| SCHEMBL7874195 | 0.89 | CTSS (0.57) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL7874192 | 0.89 | CTSS (0.57) | CTSSCTSKTSHRCA2LMNA | |
| SCHEMBL16715127 | 0.89 | CTSK (0.56) | CTSSCTSKTSHRCA2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1444194-B1 | N-METHYL-HOMOCYSTINES, USE THEREOF AND METHOD FOR THE PRODUCTION THEREOF | CIS BIO INT (FR) | 2009-12-09 | — | — | EP | disclosed |